Methyl 3-broMo-4-nitrobenzoate

Base Information

• Chemical Name: Methyl 3-broMo-4-nitrobenzoate
• CAS No.: 126759-30-6
• Molecular Formula: C8H6BrNO4
• Molecular Weight: 260.044
• Hs Code.: 2916399090
• Mol file: 126759-30-6.mol

Synonyms:Methyl 3-bromo-4-nitrobenzoate;

Chemical Property of Methyl 3-broMo-4-nitrobenzoate

Chemical Property:

• Boiling Point: 319.355 °C at 760 mmHg
• Flash Point: 146.941 °C
• PSA: 72.12000
• Density: 1.674 g/cm³
• LogP: 2.66710
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

3-Bromo-4-nitro-benzoicAcidMethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 3-broMo-4-nitrobenzoate

There total 4 articles about Methyl 3-broMo-4-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

methyl 4-amino-3-bromobenzoate (106896-49-5) → 3-bromo-4-nitrobenzoate methyl ester (126759-30-6)

Guidance literature:

With dihydrogen peroxide; trifluoroacetic acid; at 60 ℃; for 18h;

DOI:10.24820/ARK.5550190.P011.661

Reference yield:

3-bromo-4-nitrotoluene (40385-54-4) → 3-bromo-4-nitrobenzoate methyl ester (126759-30-6)

Guidance literature:

Multi-step reaction with 2 steps

1: CrO₃; acetic acid

2: HCl

With chromium(VI) oxide; hydrogenchloride; acetic acid;

DOI:10.1021/ja01157a007

Reference yield:

methanol (67-56-1) + 3-Bromo-4-nitrobenzoic acid (101420-81-9) → 3-bromo-4-nitrobenzoate methyl ester (126759-30-6)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01157a007

upstream raw materials:

methanol

3-Bromo-4-nitrobenzoic acid

3-bromo-4-nitrotoluene

4-amino-benzoic acid

Downstream raw materials:

5-methoxycarbonylindole

methyl 3-ethenyl-4-nitrobenzoate

Refernces