N,N-diethyl-3-fluoro-4-nitrobenzamide

Base Information

• Chemical Name: N,N-diethyl-3-fluoro-4-nitrobenzamide
• CAS No.: 474020-75-2
• Molecular Formula: C₁₁H₁₃FN₂O₃
• Molecular Weight: 240.234
• Mol file: 474020-75-2.mol

Synonyms:N,N-Diethyl-3-fluoro-4-nitrobenzamide;

Chemical Property of N,N-diethyl-3-fluoro-4-nitrobenzamide

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.536
• Boiling Point: 398.087 °C at 760 mmHg
• Flash Point: 194.556 °C
• PSA: 66.13000
• Density: 1.24 g/cm³
• LogP: 2.73910
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

N,N-Diethyl-3-fluoro-4-nitrobenzamide 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-diethyl-3-fluoro-4-nitrobenzamide

There total 1 articles about N,N-diethyl-3-fluoro-4-nitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-fluoro-4-nitrobenzoic acid (403-21-4) + diethylamine (109-89-7) → N,N-diethyl-3-fluoro-4-nitrobenzamide (474020-75-2)

Guidance literature:

With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

Reference yield: 100.0%

N,N-diethyl-3-fluoro-4-nitrobenzamide (474020-75-2) → 2-nitro-5-(N',N'-diethylcarbamoyl)-aniline (474020-77-4)

Guidance literature:

With ammonia; In ethanol; water; at 65 ℃;

upstream raw materials:

3-fluoro-4-nitrobenzoic acid

diethylamine

Downstream raw materials:

2-nitro-5-(N',N'-diethylcarbamoyl)-aniline

Refernces