4-(2-Hydroxyphenyl)-3-methyl-1,3-butadien

Base Information

• Chemical Name: 4-(2-Hydroxyphenyl)-3-methyl-1,3-butadien
• CAS No.: 36852-15-0
• Molecular Formula: C₁₁H₁₂O
• Molecular Weight: 160.216
• Mol file: 36852-15-0.mol

Synonyms:

Chemical Property of 4-(2-Hydroxyphenyl)-3-methyl-1,3-butadien

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2-Hydroxyphenyl)-3-methyl-1,3-butadien

There total 5 articles about 4-(2-Hydroxyphenyl)-3-methyl-1,3-butadien which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-2-(3-hydroxy-3-methylbut-1-en-1-yl)phenol (17235-15-3) → 2,2-dimethyl-2H-chromene (2513-25-9) + 4-(2-Hydroxyphenyl)-3-methyl-1,3-butadien (36852-15-0)

Guidance literature:

With [2,2]bipyridinyl; iron(III) chloride; In tetrahydrofuran; at 20 - 80 ℃; for 5h; Overall yield = 54 %; Overall yield = 43 mg; Microwave irradiation; Inert atmosphere;

DOI:10.1002/adsc.201500058

Reference yield:

(Z)-4-(o-hydroxyphenyl)-2-methylbut-3-en-2-ol (17235-14-2) → 2,2-dimethyl-2H-chromene (2513-25-9) + 4-(2-Hydroxyphenyl)-3-methyl-1,3-butadien (36852-15-0)

Guidance literature:

With [2,2]bipyridinyl; iron(III) chloride; In tetrahydrofuran; at 20 - 80 ℃; for 5h; Overall yield = 60 %; Overall yield = 48 mg; Microwave irradiation; Inert atmosphere;

DOI:10.1002/adsc.201500058

Reference yield:

2,2-dimethyl-2H-chromene (2513-25-9) → 4-(2-Hydroxyphenyl)-3-methyl-1,3-butadien (36852-15-0)

Guidance literature:

In acetone; Irradiation;

DOI:10.1021/jo00896a033

upstream raw materials:

2,2-dimethyl-2H-chromene

(E)-2-(3-hydroxy-3-methylbut-1-en-1-yl)phenol

(Z)-4-(o-hydroxyphenyl)-2-methylbut-3-en-2-ol

(E)-4-(2-hydroxyphenyl)but-3-en-2-one

Refernces