4-Benzyl-2-thiazolidinethione

Base Information

• Chemical Name: 4-Benzyl-2-thiazolidinethione
• CAS No.: 13897-15-9
• Molecular Formula: C10H11NS2
• Molecular Weight: 209.336
• Hs Code.: 2934999090
• Mol file: 13897-15-9.mol

Synonyms:2-thiazolidinethione, 4-(phenylmethyl)-;

Chemical Property of 4-Benzyl-2-thiazolidinethione

Chemical Property:

• Vapor Pressure: 0.000341mmHg at 25°C
• Refractive Index: 1.674
• Boiling Point: 329.4 °C at 760 mmHg
• PKA: 13.01±0.40(Predicted)
• Flash Point: 153 °C
• PSA: 76.46000
• Density: 1.27g/cm³
• LogP: 2.06590

Purity/Quality:

99% ^*data from raw suppliers

4-Benzyl-1,3-thiazolidine-2-thione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Benzyl-2-thiazolidinethione

There total 1 articles about 4-Benzyl-2-thiazolidinethione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + 1-bromomethyl-2-phenyl-ethylamine; hydrobromide (13892-90-5,283589-06-0) → (4S)-4-benzyl-1,3-thiazolidine-2-thione (13897-15-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1021/jm00324a027

Reference yield: 95.0%

(4S)-4-benzyl-1,3-thiazolidine-2-thione (13897-15-9) + butyryl chloride (141-75-3) → 1-(4-benzyl-2-thioxothiazolidin-3-yl)butan-1-one

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1002/ejoc.201700379

Reference yield: 90.0%

(4S)-4-benzyl-1,3-thiazolidine-2-thione (13897-15-9) + butyryl chloride (141-75-3) → 1-[(4S)-4-benzyl-2-thioxo(1,3-thiazolidin-3-yl)]butan-1-one

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1021/ol025553o

upstream raw materials:

carbon disulfide

1-bromomethyl-2-phenyl-ethylamine; hydrobromide

Downstream raw materials:

(R)-4-benzyl-thiazolidine-2-thione

(S)-4-benzylthiazolidin-2-thione

Refernces