1,2,3,4-Tetrahydronaphthalen-1-ylmethylamine

Base Information

• Chemical Name: 1,2,3,4-Tetrahydronaphthalen-1-ylmethylamine
• CAS No.: 91245-72-6
• Molecular Formula: C11H15N
• Molecular Weight: 161.247
• Hs Code.: 2921499090
• European Community (EC) Number: 815-502-2
• ChEMBL ID: CHEMBL47983
• DSSTox Substance ID: DTXSID00461536
• Nikkaji Number: J1.203.059B
• Mol file: 91245-72-6.mol

Synonyms:91245-72-6;1,2,3,4-tetrahydronaphthalen-1-ylmethylamine;(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)METHANAMINE;1,2,3,4-tetrahydronaphthalen-1-ylmethanamine;tetralin-1-ylmethanamine;C-(1,2,3,4-Tetrahydro-naphthalen-1-yl)-methylamine;1,2,3,4-TETRAHYDRO-1-NAPHTHALENEMETHANAMINE;CHEMBL47983;1-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)METHANAMINE;SCHEMBL643387;DTXSID00461536;FSEUPTSLGGJFNX-UHFFFAOYSA-N;BDBM50111531;MFCD02179233;AKOS009164173;AB11056;BS-13641;CS-0310002;FT-0742421;EN300-30476;P19863;1,2,3,4-tetrahydro-1-naphthalenemethanamine, AldrichCPR;Z234895145

Chemical Property of 1,2,3,4-Tetrahydronaphthalen-1-ylmethylamine

Chemical Property:

• Boiling Point: 272.6 °C at 760 mmHg
• PKA: 9.90±0.29(Predicted)
• Flash Point: 123.7 °C
• PSA: 26.02000
• Density: 1.001 g/cm³
• LogP: 2.76550
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 161.120449483
• Heavy Atom Count: 12
• Complexity: 144

Purity/Quality:

99% ^*data from raw suppliers

1,2,3,4-tetrahydronaphthalen-1-ylmethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(C2=CC=CC=C2C1)CN

Technology Process of 1,2,3,4-Tetrahydronaphthalen-1-ylmethylamine

There total 9 articles about 1,2,3,4-Tetrahydronaphthalen-1-ylmethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

1-aminomethyl-1-hydroxy-1,2,3,4-tetrahydronaphthalene (50361-60-9) → (+/-)-1-(aminomethyl)-1,2,3,4-tetrahydronaphthalene (91245-72-6)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1021/jm00107a025

Reference yield:

(+/-)-1-(aminomethyl)-1-hydroxy-1,2,3,4-tetrahydronaphthalene hydrochloride (80096-56-6) → (+/-)-1-(aminomethyl)-1,2,3,4-tetrahydronaphthalene (91245-72-6)

Guidance literature:

With perchloric acid; hydrogen; palladium on activated charcoal; In ethanol; under 2585.7 Torr;

DOI:10.1021/jm00346a012

Reference yield:

1,2,3,4-tetrahydro-1-naphthalenecarbaldehyde (155566-54-4,18278-24-5) → (+/-)-1-(aminomethyl)-1,2,3,4-tetrahydronaphthalene (91245-72-6)

Guidance literature:

With ammonia; hydrogen; nickel; In ethanol; under 36775.4 Torr;

DOI:10.1016/S0040-4020(01)98625-9

upstream raw materials:

1-Cyanonaphthalene

1-aminomethyl-1-hydroxy-1,2,3,4-tetrahydronaphthalene

(+/-)-1-(aminomethyl)-1-hydroxy-1,2,3,4-tetrahydronaphthalene hydrochloride

1,2,3,4-tetrahydro-1-naphthalenecarbaldehyde

Downstream raw materials:

(E)-N-methyl-N-(3-phenyl-2-propenyl)-1,2,3,4-tetrahydro-1-naphthalenemethanamine

oxalic acid

benzene-1,2-dicarboxylic acid

Refernces

• 1、 Trivedi, B. K.,Blankley, C. J.,Bristol, J. A.,Hamilton, H. W.,Patt, W. C.,et al.. "N6-Substituted Adenosine Receptor Agonists: Potential AntihypertensiveAgents". . p. 1043 - 1049. Retrieved 2007/10/02.