N-2-(2-Nitrophenyl)aethylsarcosin

Base Information

• Chemical Name: N-2-(2-Nitrophenyl)aethylsarcosin
• CAS No.: 33100-20-8
• Molecular Formula: C₁₁H₁₄N₂O₄
• Molecular Weight: 238.243
• Mol file: 33100-20-8.mol

Synonyms:

Chemical Property of N-2-(2-Nitrophenyl)aethylsarcosin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-2-(2-Nitrophenyl)aethylsarcosin

There total 5 articles about N-2-(2-Nitrophenyl)aethylsarcosin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitro-benzeneethanol (15121-84-3) → N-2-(2-Nitrophenyl)aethylsarcosin (33100-20-8)

Guidance literature:

Multi-step reaction with 4 steps

1: aq. HBr

2: (i) aq. NaN₃, DMSO, (ii) Ph₃P, benzene, (iii) aq. HBr, AcOH

3: acetonitrile

4: (i) K₂CO₃, MeCN, (ii) aq. HBr

With hydrogen bromide; In acetonitrile;

DOI:10.1139/v71-329

Reference yield:

ethyl 2-nitrophenylacetate (31912-02-4) → N-2-(2-Nitrophenyl)aethylsarcosin (33100-20-8)

Guidance literature:

Multi-step reaction with 5 steps

1: NaBH₄, AlCl₃

2: aq. HBr

3: (i) aq. NaN₃, DMSO, (ii) Ph₃P, benzene, (iii) aq. HBr, AcOH

4: acetonitrile

5: (i) K₂CO₃, MeCN, (ii) aq. HBr

With sodium tetrahydroborate; aluminium trichloride; hydrogen bromide; In acetonitrile;

DOI:10.1139/v71-329

Reference yield:

(2-bromoethyl)-2-nitrobenzene (16793-89-8) → N-2-(2-Nitrophenyl)aethylsarcosin (33100-20-8)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) aq. NaN₃, DMSO, (ii) Ph₃P, benzene, (iii) aq. HBr, AcOH

2: acetonitrile

3: (i) K₂CO₃, MeCN, (ii) aq. HBr

In acetonitrile;

DOI:10.1139/v71-329

upstream raw materials:

methyl-(2-nitro-phenethyl)-amine

ethyl bromoacetate

2-nitro-benzeneethanol

(2-bromoethyl)-2-nitrobenzene