2-methoxycarbonyl-2-methylpropyl methyl (E)-2,3-dibromobut-2-enedioate

Base Information

• Chemical Name: 2-methoxycarbonyl-2-methylpropyl methyl (E)-2,3-dibromobut-2-enedioate
• CAS No.: 419561-89-0
• Molecular Formula: C₁₁H₁₄Br₂O₆
• Molecular Weight: 402.037
• Mol file: 419561-89-0.mol

Synonyms:

Chemical Property of 2-methoxycarbonyl-2-methylpropyl methyl (E)-2,3-dibromobut-2-enedioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methoxycarbonyl-2-methylpropyl methyl (E)-2,3-dibromobut-2-enedioate

There total 1 articles about 2-methoxycarbonyl-2-methylpropyl methyl (E)-2,3-dibromobut-2-enedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

methanol (67-56-1) + (2E)-dibromobut-2-enedioyl dichloride (44873-83-8) + Methyl 2,2-dimethyl-3-hydroxypropionate (14002-80-3) → 2-methoxycarbonyl-2-methylpropyl methyl (E)-2,3-dibromobut-2-enedioate (419561-89-0)

Guidance literature:

With pyridine; In tetrachloromethane; at 0 ℃;

DOI:10.1002/1099-0690(200112)2001:24<4705::AID-EJOC4705>3.0.CO;2-J

Reference yield: 77.0%

2-methoxycarbonyl-2-methylpropyl methyl (E)-2,3-dibromobut-2-enedioate (419561-89-0) → 2-methoxycarbonyl-2-methylpropyl methyl but-2-ynedioate (419561-98-1)

Guidance literature:

With zinc; In tetrahydrofuran; for 3.5h; Heating;

DOI:10.1002/1099-0690(200112)2001:24<4705::AID-EJOC4705>3.0.CO;2-J

Reference yield:

2-methoxycarbonyl-2-methylpropyl methyl (E)-2,3-dibromobut-2-enedioate (419561-89-0) → 1-(1-methoxycarbonyl-2,2-dimethylethyl) 2-methyl 3,3-dimethyl-1-cyclopropene-1,2-dicarboxylate

Guidance literature:

Multi-step reaction with 2 steps

1.1: 77 percent / zinc / tetrahydrofuran / 3.5 h / Heating

2.1: diethyl ether; CH₂Cl₂

2.2: diethyl ether / Irradiation

With zinc; In tetrahydrofuran; diethyl ether; dichloromethane;

DOI:10.1002/1099-0690(200112)2001:24<4705::AID-EJOC4705>3.0.CO;2-J

upstream raw materials:

methanol

(2E)-dibromobut-2-enedioyl dichloride

Methyl 2,2-dimethyl-3-hydroxypropionate

Downstream raw materials:

2-methoxycarbonyl-2-methylpropyl methyl but-2-ynedioate

Refernces