C₁₆H₂₂BrNO₃

Base Information

• Chemical Name: C₁₆H₂₂BrNO₃
• CAS No.: 1467720-17-7
• Molecular Formula: C₁₆H₂₂BrNO₃
• Molecular Weight: 356.26
• Mol file: 1467720-17-7.mol

Synonyms:

Chemical Property of C₁₆H₂₂BrNO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₂₂BrNO₃

There total 1 articles about C₁₆H₂₂BrNO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(3-phenoxypropyl)morpholine (100618-57-3) + 3-Bromopropionyl chloride (15486-96-1) → C16H22BrNO3 (1467720-17-7)

Guidance literature:

With aluminum (III) chloride; In dichloromethane; at 0 - 20 ℃; for 2h;

DOI:10.5012/bkcs.2013.34.8.2317

Reference yield:

C16H22BrNO3 (1467720-17-7) → C16H24BrNO3

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; for 1h;

DOI:10.5012/bkcs.2013.34.8.2317

Reference yield:

C16H22BrNO3 (1467720-17-7) → 1-(4-(3-morpholinopropoxy)phenyl)-3-aminopropan-1-ol

Guidance literature:

Multi-step reaction with 3 steps

1: sodium tetrahydroborate / methanol / 1 h / 0 - 20 °C

2: sodium azide / N,N-dimethyl-formamide / 4 h / 80 °C

3: lithium aluminium tetrahydride / tetrahydrofuran; diethyl ether / 1 h / 0 - 20 °C

With sodium tetrahydroborate; lithium aluminium tetrahydride; sodium azide; In tetrahydrofuran; methanol; diethyl ether; N,N-dimethyl-formamide;

DOI:10.5012/bkcs.2013.34.8.2317

upstream raw materials:

4-(3-phenoxypropyl)morpholine

3-Bromopropionyl chloride

Downstream raw materials:

1-[3-{4-(3-morpholinopropoxy)phenyl}-3-hydroxypropyl]-3-isopropylthiourea

1-[3-{4-(3-morpholinopropoxy)phenyl}-3-hydroxypropyl]-3-phenylthiourea

1-[3-{4-(3-morpholinopropoxy)phenyl}-3-hydroxypropyl]-3-methylthiourea

Refernces