D-myo-inositol 4-phosphate biscyclohexylammonium salt

Base Information

• Chemical Name: D-myo-inositol 4-phosphate biscyclohexylammonium salt
• CAS No.: 14980-89-3
• Molecular Formula: 2C₆H₁₃N*C₆H₁₃O₉P
• Molecular Weight: 458.489
• Mol file: 14980-89-3.mol

Synonyms:

Chemical Property of D-myo-inositol 4-phosphate biscyclohexylammonium salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of D-myo-inositol 4-phosphate biscyclohexylammonium salt

There total 23 articles about D-myo-inositol 4-phosphate biscyclohexylammonium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C56H59N2O13P (1447464-01-8) + cyclohexylamine (108-91-8,157973-60-9) → D-myo-inositol-3-phosphate biscyclohexylamine salt (14980-89-3,15065-15-3,16006-20-5,32739-43-8,37170-04-0,53797-24-3,70470-66-5,103529-92-6,106032-58-0,106032-59-1,106707-92-0,111956-21-9,114884-35-4,125356-28-7,126722-33-6)

Guidance literature:

C₅₆H₅₉N₂O₁₃P; With N,O-Bis(trimethylsilyl)trifluoroacetamide; In dichloromethane; at 0 ℃; for 0.0333333h; Inert atmosphere;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 0 ℃; for 0.333333h; Inert atmosphere;

cyclohexylamine; Further stages;

DOI:10.1002/anie.201301092

Reference yield: 36.0%

Phosphoric acid mono-((1R,2R,3R,4S,5R,6S)-2,5-bis-benzyloxy-3,4,6-trihydroxy-cyclohexyl) ester; compound with cyclohexylamine → cyklohexylammonium salt of 4(6)-O-phospho-sn-myoinositol (14980-89-3,15065-15-3,16006-20-5,32739-43-8,37170-04-0,53797-24-3,70470-66-5,103529-92-6,106032-58-0,106032-59-1,106707-92-0,111956-21-9,114884-35-4,125356-28-7,126722-33-6)

Guidance literature:

With hydrogen; palladium; In methanol; water;

Reference yield:

cyclohexylamine (108-91-8,157973-60-9) + (+)-2,4,6-tri-O-benzyl-myo-inositol-3-phosphate (474404-92-7) → D-myo-inositol-3-phosphate biscyclohexylamine salt (14980-89-3,15065-15-3,16006-20-5,32739-43-8,37170-04-0,53797-24-3,70470-66-5,103529-92-6,106032-58-0,106032-59-1,106707-92-0,111956-21-9,114884-35-4,125356-28-7,126722-33-6)

Guidance literature:

(+)-2,4,6-tri-O-benzyl-myo-inositol-3-phosphate; With ammonia; lithium; In tetrahydrofuran; at -78 ℃; for 0.75h;

cyclohexylamine; In water; for 1h; Further stages.;

DOI:10.1021/ja027402m

upstream raw materials:

D-myo-inositol-3-phosphate

cyclohexylamine

(+)-2,4,6-tri-O-benzyl-myo-inositol-3-phosphate

2,4,6-tri-O-benzyl-myo-inositol

Refernces

• 1、 Capolicchio, Samanta,Thakor, Divyeshsinh T.,Linden, Anthony,Jessen, Henning J.. "Synthesis of unsymmetric diphospho-inositol polyphosphates". supporting information. p. 6912 - 6916. Retrieved 2013/07/26.
• 2、 Spiers, Ian D.,Schwalbe, Carl H.,Blake, Alexander J.,Solomons, Kevin R.H.,Freeman, Sally. "Structure of (±)-1,2;4,5-di-o-cyclohexylidene myo-inositol and synthesis of myo-inositol 3-phosphate via its phosphorylation with (2R,4S,5R)-2-chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidin-2-one". . p. 43 - 51. Retrieved 2007/10/03.