N-Cbz-cis-4-Hydroxy-L-proline methyl ester

Base Information Edit

Chemical Name:N-Cbz-cis-4-Hydroxy-L-proline methyl ester
CAS No.:57653-35-7
Molecular Formula:C14H17NO5
Molecular Weight:279.293
Hs Code.:
European Community (EC) Number:613-498-5,693-601-8
Mol file:57653-35-7.mol

Synonyms:57653-35-7;N-Cbz-cis-4-Hydroxy-L-proline methyl ester;(2S,4S)-1-Benzyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate;1-O-benzyl 2-O-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate;MFCD09954934;(2S,4S)-1-(Benzyloxycarbonyl)-2-(methoxycarbonyl)-4-hydroxypyrrolidine;CIS-ZHPROME;SCHEMBL1448027;64187-48-0;AKOS025146558;DS-8948;CS-0048816;EN300-7070691;A869625;AU-004/43510498;N-Cbz-cis-4-Hydroxy-L-proline methyl ester, 97%;1-CBZ-CIS-4-HYDROXY-L-PROLINE METHYL ESTER;cis-N-Carbobenzyloxy-4-hydroxy-L-proline, methyl ester;N-benzyloxycarbonyl-4-hydroxy-L-cis-proline methyl ester;N-Carbobenzyloxy-cis-4-hydroxy-L-proline, methyl ester;1-benzyl 2-methyl 4-hydroxy-1,2-pyrrolidinedicarboxylate;(cis)-1-benzyloxycarbonyl-4-hydroxy-L-proline, methyl ester;(2S,4S)-1-Benzyl2-methyl4-hydroxypyrrolidine-1,2-dicarboxylate;1-benzyl 2-methyl(2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate;1-BENZYL 2-METHYL (2S,4S)-4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE;O1-benzyl O2-methyl (2S,4S)-4-hydroxypyrrolidine-1,2-dicarboxylate

Suppliers and Price of N-Cbz-cis-4-Hydroxy-L-proline methyl ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Cbz-cis-4-Hydroxy-L-proline methyl ester
1g
$ 100.00

SynQuest Laboratories
N-Cbz-cis-4-hydroxy-L-proline methyl ester 97.0%
5 g
$ 540.00

SynQuest Laboratories
N-Cbz-cis-4-hydroxy-L-proline methyl ester 97.0%
25 g
$ 890.00

SynQuest Laboratories
N-Cbz-cis-4-hydroxy-L-proline methyl ester 97.0%
250 mg
$ 90.00

SynQuest Laboratories
N-Cbz-cis-4-hydroxy-L-proline methyl ester 97.0%
1 g
$ 190.00

Sigma-Aldrich
N-Cbz-cis-4-Hydroxy-L-proline methyl ester 97%
1g
$ 184.00

Crysdot
(2S,4S)-1-Benzyl2-methyl4-hydroxypyrrolidine-1,2-dicarboxylate 95+%
10g
$ 158.00

Arctom
(2S,4S)-1-Benzyl2-methyl4-hydroxypyrrolidine-1,2-dicarboxylate 97%
5g
$ 85.00

Arctom
(2S,4S)-1-Benzyl2-methyl4-hydroxypyrrolidine-1,2-dicarboxylate 97%
25g
$ 262.00

Arctom
(2S,4S)-1-Benzyl2-methyl4-hydroxypyrrolidine-1,2-dicarboxylate 97%
1g
$ 27.00

Total 17 raw suppliers

Chemical Property of N-Cbz-cis-4-Hydroxy-L-proline methyl ester Edit

Chemical Property:

Melting Point:80-85°C
Boiling Point:422.8±45.0 °C(Predicted)
PKA:14.25±0.40(Predicted)
PSA：76.07000
Density:1.313±0.06 g/cm3(Predicted)
LogP:0.86930
Storage Temp.:2-8°C
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:279.11067264
Heavy Atom Count:20
Complexity:354

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Cbz-cis-4-Hydroxy-L-proline methyl ester ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1CC(CN1C(=O)OCC2=CC=CC=C2)O
Isomeric SMILES:COC(=O)[C@@H]1C[C@@H](CN1C(=O)OCC2=CC=CC=C2)O

Technology Process of N-Cbz-cis-4-Hydroxy-L-proline methyl ester

There total 24 articles about N-Cbz-cis-4-Hydroxy-L-proline methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%