4-Bromo-3-phenylisothiazole

Base Information

• Chemical Name: 4-Bromo-3-phenylisothiazole
• CAS No.: 16187-94-3
• Molecular Formula: C₉H₆BrNS
• Molecular Weight: 240.123
• Mol file: 16187-94-3.mol

Synonyms:

Chemical Property of 4-Bromo-3-phenylisothiazole

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Bromo-3-phenylisothiazole

There total 6 articles about 4-Bromo-3-phenylisothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-phenylisothiazole (10514-34-8) → 4-bromo-3-phenyl-isothiazole (16187-94-3)

Guidance literature:

With bromine; sodium acetate; In acetic acid; for 2h; Heating;

Reference yield:

5-amino-3-phenylisothiazole (14208-52-7) → 4-bromo-3-phenyl-isothiazole (16187-94-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Br₂ / acetic acid; benzene

2: (i) aq. NaNO₂, H₂SO₄, H₃PO₄, (ii) aq. H₃PO₂, Cu₂O

With bromine; In acetic acid; benzene;

Reference yield:

3-phenyl-3-iminothiopropionamide (16187-91-0) → 4-bromo-3-phenyl-isothiazole (16187-94-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Br₂ / ethanol / 2 h / 10 °C

2: (i) aq. NaNO₂, H₂SO₄, H₃PO₄, (ii) aq. H₃PO₂, Cu₂O

With bromine; In ethanol;

upstream raw materials:

4-bromo-3-phenyl-isothiazol-5-ylamine

3-phenylisothiazole

5-amino-3-phenylisothiazole

3-phenyl-3-iminothiopropionamide

Downstream raw materials:

4-cyano-3-phenylisothiazole

4-bromo-3-(3-nitro-phenyl)-isothiazole

3-phenylisothiazole

5-methyl-3-phenyl-isothiazole-4-carboxylic acid