5-bromo-4-chloropyridine-2,3-diamine

Base Information

• Chemical Name: 5-bromo-4-chloropyridine-2,3-diamine
• CAS No.: 1131604-99-3
• Molecular Formula: C5H5BrClN3
• Molecular Weight: 222.4703
• Hs Code.: 2933399990
• Mol file: 1131604-99-3.mol

Synonyms:TC-010216;

Chemical Property of 5-bromo-4-chloropyridine-2,3-diamine

Chemical Property:

• Melting Point: 164℃
• Boiling Point: 333.676 °C at 760 mmHg
• PKA: 3.50±0.50(Predicted)
• Flash Point: 155.602 °C
• PSA: 65.66000
• Density: 1.929 g/cm³
• LogP: 2.17320
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Bromo-4-chloropyridine-2,3-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-bromo-4-chloropyridine-2,3-diamine

There total 3 articles about 5-bromo-4-chloropyridine-2,3-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-bromo-4-chloro-3-nitro-pyridin-2-ylamine (942947-95-7) → C5H5BrClN3 (1131604-99-3)

Guidance literature:

With acetic acid; zinc; at 20 ℃; for 3.33333h;

DOI:10.1016/j.ejmech.2016.04.017

Reference yield:

2-Amino-4-chloropyridine (19798-80-2) → C5H5BrClN3 (1131604-99-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: N-Bromosuccinimide / acetonitrile / 24 h / 20 °C

2.1: sulfuric acid / -5 °C

2.2: 3.08 h / 0 - 50 °C

3.1: zinc; acetic acid / 3.33 h / 20 °C

With N-Bromosuccinimide; sulfuric acid; acetic acid; zinc; In acetonitrile;

DOI:10.1016/j.ejmech.2016.04.017

Reference yield:

5-bromo-4-chloro-pyridin-2-ylamine (942947-94-6) → C5H5BrClN3 (1131604-99-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sulfuric acid / -5 °C

1.2: 3.08 h / 0 - 50 °C

2.1: zinc; acetic acid / 3.33 h / 20 °C

With sulfuric acid; acetic acid; zinc;

DOI:10.1016/j.ejmech.2016.04.017

upstream raw materials:

5-bromo-4-chloro-pyridin-2-ylamine

2-Amino-4-chloropyridine

5-bromo-4-chloro-3-nitro-pyridin-2-ylamine

Downstream raw materials:

C₂₃H₂₆N₆O₂

C₃₀H₃₇N₇O₃S

C₂₆H₂₉N₇O₃S

C₂₆H₂₈N₆O₄S

Refernces