Technology Process of C37H42F3N3O4
There total 9 articles about C37H42F3N3O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(R)-Norfluoxetine;
With
sodium hydride;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.333333h;
2-(2-bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,6,7,8,8a-hexahydrophthalazin-1(2H)-one;
In
N,N-dimethyl-formamide;
at 20 ℃;
DOI:10.1016/j.bmc.2008.10.065
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: tetrahydrofuran / 0 - 20 °C
1.2: pH 2
2.1: hydrazine hydrate / ethanol / Reflux
3.1: sodium hydride / mineral oil / 0.5 h / 20 °C
3.2: 0.5 h / 20 °C
4.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h / 20 °C
4.2: 20 °C
With
sodium hydride; hydrazine hydrate;
In
tetrahydrofuran; ethanol; N,N-dimethyl-formamide; mineral oil;
1.1: Grignard reaction / 1.2: Grignard reaction;
DOI:10.1016/j.bmc.2008.10.065
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: sodium iodide / dimethyl sulfoxide / 13 h / 70 °C
3.1: hydrazine hydrate / methanol; dichloromethane / 8 h / 20 °C
4.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h / 20 °C
4.2: 20 °C
With
di-isopropyl azodicarboxylate; sodium hydride; hydrazine hydrate; triphenylphosphine; sodium iodide;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
1.1: Mitsunobu reaction / 1.2: Mitsunobu reaction;
DOI:10.1016/j.bmc.2008.10.065