3,6-Dibromoquinoline

Base Information

• Chemical Name: 3,6-Dibromoquinoline
• CAS No.: 69268-39-9
• Molecular Formula: C9H5Br2N
• Molecular Weight: 286.953
• Hs Code.: 2933499090
• European Community (EC) Number: 694-872-5
• DSSTox Substance ID: DTXSID30357019
• Wikidata: Q82136701
• ChEMBL ID: CHEMBL1458274
• Mol file: 69268-39-9.mol

Synonyms:3,6-dibromoquinoline;69268-39-9;3,6-Dibromo-quinoline;BAS 00280897;MLS000568650;CHEMBL1458274;SCHEMBL20528292;DTXSID30357019;HMS2533G09;MFCD00464317;AKOS016007528;SB21397;BS-49459;SMR000174223;SY157076;CS-0188407;FT-0752538;E78286;EN300-132364;Z1269114696

Chemical Property of 3,6-Dibromoquinoline

Chemical Property:

• Vapor Pressure: 0.000271mmHg at 25°C
• Refractive Index: 1.698
• Boiling Point: 333.1 °C at 760 mmHg
• Flash Point: 155.2 °C
• PSA: 12.89000
• Density: 1.923 g/cm³
• LogP: 3.75980
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 286.87682
• Heavy Atom Count: 12
• Complexity: 163

Purity/Quality:

98% or more ^*data from raw suppliers

3,6-Dibromoquinoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=NC=C(C=C2C=C1Br)Br

Technology Process of 3,6-Dibromoquinoline

There total 3 articles about 3,6-Dibromoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

quinoline (91-22-5) → 3-bromoquinoline (5332-24-1) + 3,6-dibromoquinoline (69268-39-9) + 3,5,6,8-tetrabromo-quinoline (136877-28-6) + 3,6,8-Tribromo-4-chloroquinoline (136877-27-5)

Guidance literature:

With bromine; In thionyl chloride; for 28h; Further byproducts given; Heating;

Reference yield:

quinoline hydrochloride (530-64-3) → 3-bromoquinoline (5332-24-1) + 3,6-dibromoquinoline (69268-39-9)

Guidance literature:

With water; bromine; at 180 ℃; im Rohr;

Reference yield:

quinoline (91-22-5) + water (7732-18-5) + bromine (7726-95-6) → 3-bromoquinoline (5332-24-1) + 3,6-dibromoquinoline (69268-39-9)

Guidance literature:

at 180 ℃; beim Erhitzen des Hydrochlorids;

upstream raw materials:

quinoline hydrochloride

quinoline

water

bromine

Downstream raw materials:

5-Bromo-pyridine-2,3-dicarboxylic acid

Refernces