MCLA

Base Information

• Chemical Name: MCLA
• CAS No.: 128322-44-1
• Molecular Formula: C14H12N3O2^.HCl
• Molecular Weight: 291.737
• Hs Code.: 2933990090
• Mol file: 128322-44-1.mol

Synonyms:6-(4-Methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one hydrochloride (1:1);imidazo[1,2-a]pyrazin-3(7H)-one, 6-(4-methoxyphenyl)-2-methyl-, hydrochloride (1:1);

Chemical Property of MCLA

Chemical Property:

• Vapor Pressure: 3.95E-07mmHg at 25°C
• Boiling Point: 410.3 °C at 760 mmHg
• Flash Point: 201.9 °C
• PSA: 59.39000
• LogP: 2.80860
• Storage Temp.: Refrigerator
• Solubility.: DMSO: soluble

Purity/Quality:

98% ^*data from raw suppliers

MCLA Hydrochloride ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: MCLA Hydrochloride is used to detect superoxide generated by activated leukocytes and macrophages. Emits chemiluminescence near 654 nm by reaction with superoxide singlet oxygen.

Technology Process of MCLA

There total 1 articles about MCLA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

2-amino-5-(4'-methoxyphenyl)-1,4-pyrazine (119738-50-0) + 2-oxopropanal (78-98-8) → 6-(4-methoxyphenyl)-2-methylimidazo<1,2-a>pyrazin-3(7H)-one hydrochloride (128322-44-1)

Guidance literature:

With hydrogenchloride; In methanol; water; at 70 ℃; for 1.5h;

DOI:10.1246/bcsj.65.2475

upstream raw materials:

2-amino-5-(4'-methoxyphenyl)-1,4-pyrazine

2-oxopropanal

Refernces

• 1、 Toya,Kayano,Sato,Goto. "Synthesis and chemiluminescence properties of 6-(4-methoxyphenyl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one and 2-methyl-6-(2-naphthyl)imidazo[1,2-a]pyrazin-3(7H)-one". . p. 2475 - 2479. Retrieved 2007/10/02.