6-Bromo-2,4'-bipyridine

Base Information

• Chemical Name: 6-Bromo-2,4'-bipyridine
• CAS No.: 106047-29-4
• Molecular Formula: C10H7BrN2
• Molecular Weight: 235.083
• DSSTox Substance ID: DTXSID60543423
• Mol file: 106047-29-4.mol

Synonyms:6-bromo-2,4'-bipyridine;106047-29-4;6-Bromo-2-(pyridin-4-yl)pyridine;2-bromo-6-pyridin-4-ylpyridine;2-bromo-6-(pyridin-4-yl)pyridine;6-bromo-2,4' -bipyridine;2,4'-Bipyridine, 6-bromo-;6-bromo-2,4'-bipyridinyl;6-bromo-[2,4']bipyridine;SCHEMBL2502957;DTXSID60543423;IXUHRYXJBJYQTQ-UHFFFAOYSA-N;MFCD11869548;AKOS014985399;DS-6108;CS-0156805;C71240;J-518316

Chemical Property of 6-Bromo-2,4'-bipyridine

Chemical Property:

• PSA: 25.78000
• LogP: 2.90610
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 233.97926
• Heavy Atom Count: 13
• Complexity: 157

Purity/Quality:

99% ^*data from raw suppliers

6-Bromo-2-(pyridin-4-yl)pyridine 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NC(=C1)Br)C2=CC=NC=C2

Technology Process of 6-Bromo-2,4'-bipyridine

There total 3 articles about 6-Bromo-2,4'-bipyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

2,6-Dibromopyridine (626-05-1) + 4-pyridylboronic acid (1692-15-5) → 2-bromo-6-(pyridin-4-yl)pyridine (106047-29-4)

Guidance literature:

With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; water; at 80 ℃; for 5h;

Reference yield: 57.0%

2,6-Dibromopyridine (626-05-1) + diethyl (pyridin-4-yl)borane (93830-58-1) → 2-bromo-6-(pyridin-4-yl)pyridine (106047-29-4)

Guidance literature:

With potassium hydroxide; tetrabutylammomium bromide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; for 3h; Heating;

DOI:10.1248/cpb.33.4755

Reference yield:

→ 2-bromo-6-(pyridin-4-yl)pyridine (106047-29-4)

Guidance literature:

upstream raw materials:

2,6-Dibromopyridine

diethyl (pyridin-4-yl)borane

4-pyridylboronic acid

Downstream raw materials:

N-(3-methylphenyl)-6-(4-pyridinyl)-2-pyridinamine

C₁₆H₁₁BrN₂

Refernces

• 1、 -. "CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE CONDENSED-CYCLIC COMPOUND". Page/Page column. . Retrieved 2014/04/03.
• 2、 -. "Phenanthro[2,3-b]pyrroles and Phenanthro[3,2-b]pyrroles for organic light-emitting devices". Page/Page column 23. . Retrieved 2011/04/18.