proanthocyanidin B₅

Base Information

• Chemical Name: proanthocyanidin B₅
• CAS No.: 88314-66-3
• Molecular Formula: C₃₀H₂₆O₁₂
• Molecular Weight: 578.529
• Mol file: 88314-66-3.mol

Synonyms:

Chemical Property of proanthocyanidin B₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of proanthocyanidin B₅

There total 2 articles about proanthocyanidin B₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol (490-46-0) → catechin-(4α->8)-ent-epicatechin (88314-66-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 2.3 g / 5percent sodium hydroxide / H₂O / 0.17 h / 65 °C

2: 1.) sodium borohydride, 2.) 0.1 M hydrochloric acid / 1.) ethanol, room temperature, 1 h, 2.) 1 h

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; In water;

Reference yield:

(-)-catechin (154-23-4,18829-70-4) + taxifolin (480-18-2,17654-26-1,5117-01-1) → catechin-(4α->8)-ent-epicatechin (88314-66-3)

Guidance literature:

With hydrogenchloride; sodium tetrahydroborate; Yield given. Multistep reaction; 1.) ethanol, room temperature, 1 h, 2.) 1 h;

Reference yield:

proanthocyanidin B5 (2271-17-2,15514-06-4,20315-25-7,20555-01-5,23567-23-9,29106-49-8,29106-51-2,35356-33-3,35356-34-4,41365-27-9,51196-37-3,51196-38-4,61505-38-2,67253-04-7,71328-22-8,82262-98-4,82262-99-5,88314-64-1,88314-66-3,120020-01-1,121842-80-6) → cyanidin

Guidance literature:

With hydrogenchloride; In methanol; for 0.333333h; Heating;

DOI:10.1007/BF00580458

upstream raw materials:

(-)-catechin

taxifolin

(2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol

Downstream raw materials:

Acetic acid (2R,3S,4R,2'S,3'R)-3,5,7,3',5'-pentaacetoxy-2,2'-bis-(3,4-diacetoxy-phenyl)-3,4,3',4'-tetrahydro-2H,2'H-[4,8']bichromenyl-7'-yl ester

Refernces