2-deoxy-D-arabino-hexose propylene dithioacetal

Base Information

• Chemical Name: 2-deoxy-D-arabino-hexose propylene dithioacetal
• CAS No.: 91294-63-2
• Molecular Formula: C₉H₁₈O₄S₂
• Molecular Weight: 254.372
• Mol file: 91294-63-2.mol

Synonyms:

Chemical Property of 2-deoxy-D-arabino-hexose propylene dithioacetal

Chemical Property:

• Boiling Point: 545.9±50.0 °C(Predicted)
• PKA: 13.57±0.20(Predicted)
• Density: 1.385±0.06 g/cm3(Predicted)
• Solubility.: DMSO, Methanol

Purity/Quality:

98% ^*data from raw suppliers

2-Deoxy-D-arabino-hexose propylene dithioacetal ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-Deoxy-D-arabino-hexose Propylene Dithioacetal (cas# 91294-63-2) is a compound useful in organic synthesis.

Technology Process of 2-deoxy-D-arabino-hexose propylene dithioacetal

There total 2 articles about 2-deoxy-D-arabino-hexose propylene dithioacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.2%

1.3-propanedithiol (109-80-8) + 2-deoxy-D-glucose (13299-15-5) → 2-deoxy-D-arabino-hexose propylene dithioacetal (91294-63-2)

Guidance literature:

With hydrogenchloride; In ethanol; at -40 - 20 ℃; for 17h;

DOI:10.1016/0008-6215(94)84211-6

Reference yield: 86.0%

1.3-propanedithiol (109-80-8) + 2-deoxy-D-arabino-hexopyranose (61-58-5,13299-15-5,13299-16-6,14215-77-1,14215-78-2,20789-85-9,23568-30-1,25494-04-6,34339-39-4,34339-40-7,34339-46-3,34339-47-4,114717-20-3,114717-21-4,137491-75-9,137491-76-0) → 2-deoxy-D-arabino-hexose propylene dithioacetal (91294-63-2)

Guidance literature:

With hydrogenchloride; In ethanol; at 25 ℃;

DOI:10.1021/ja00285a022

Reference yield:

2-deoxy-D-arabino-hexose propylene dithioacetal (91294-63-2) → methyl (methyl 3-deoxy-α-D-arabino-2-heptulopyranosid)onate (2880-95-7,85549-51-5)

Guidance literature:

Multi-step reaction with 3 steps

1: cc. sulfuric acid / 25 °C

3: 94 percent / 1 M HCl / methanol / Heating

With hydrogenchloride; sulfuric acid; In methanol;

DOI:10.1021/ja00285a022

upstream raw materials:

1.3-propanedithiol

2-deoxy-D-arabino-hexopyranose

2-deoxy-D-glucose

Downstream raw materials:

2-deoxy-3,4:5,6-di-O-isopropylidene-D-arabino-hexose propylene dithioacetal

methyl (methyl 3-deoxy-α-D-arabino-2-heptulopyranosid)onate

Refernces