5-Bromo-2,3,4-trimethoxybenzaldehyde

Base Information

• Chemical Name: 5-Bromo-2,3,4-trimethoxybenzaldehyde
• CAS No.: 28006-94-2
• Molecular Formula: C10H11BrO4
• Molecular Weight: 275.099
• Hs Code.: 2913000090
• DSSTox Substance ID: DTXSID00544717
• Nikkaji Number: J1.326.987D
• Wikidata: Q82421951
• Mol file: 28006-94-2.mol

Synonyms:5-Bromo-2,3,4-trimethoxybenzaldehyde;28006-94-2;5-Bromo-2,3,4-trimethoxy-benzaldehyde;DTXSID00544717;5-bromo-2, 3, 4-trimethoxybenzaldehyde

Chemical Property of 5-Bromo-2,3,4-trimethoxybenzaldehyde

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 349.54°C at 760 mmHg
• Flash Point: 165.196°C
• PSA: 44.76000
• Density: 1.453g/cm³
• LogP: 2.28740
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 273.98407
• Heavy Atom Count: 15
• Complexity: 212

Purity/Quality:

99%, ^*data from raw suppliers

5-BROMO-2,3,4-TRIMETHOXYBENZALDEHYDE 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C(=C(C=C1C=O)Br)OC)OC

Technology Process of 5-Bromo-2,3,4-trimethoxybenzaldehyde

There total 2 articles about 5-Bromo-2,3,4-trimethoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2,3,4-trimethoxybenzaldehyde (2103-57-3) → 5-bromo-2,3,4-trimethoxybenzaldehyde (28006-94-2)

Guidance literature:

With bromine; acetic acid; at 20 ℃; for 24h;

DOI:10.1021/jm701358v

Reference yield:

→ 5-bromo-2,3,4-trimethoxybenzaldehyde (28006-94-2)

Guidance literature:

Dibromverb. 3, CH3(CH2)3Li, HCO-N(CH3)2;

DOI:10.1039/j39700000227

Reference yield:

5-bromo-2,3,4-trimethoxybenzaldehyde (28006-94-2) + ethylene glycol (107-21-1) → C12H15BrO5

Guidance literature:

With toluene-4-sulfonic acid; In toluene; at 20 ℃; Heating;

DOI:10.1021/jm701358v

upstream raw materials:

2,3,4-trimethoxybenzaldehyde

Downstream raw materials:

C₂₁H₂₀BrNO₅

imeluteine

Refernces

• 1、 Tang, Guozhi,Nikolovska-Coleska, Zaneta,Qiu, Su,Yang, Chao-Yie,Guo, Jie,Wang, Shaomeng. "Acylpyrogallols as inhibitors of antiapoptotic Bcl-2 proteins". . p. 717 - 720. Retrieved 2008/09/18.
• 2、 Nakanishi,Suzuki. "Synthesis and cytotoxic activities of a new benzo[c]phenanthridine alkaloid, 7-hydroxynitidine, and some 9-oxygenated benzo[c]phenanthridine derivatives.". . p. 985 - 988. Retrieved 2008/02/09.