dibenzyl 2-(dibenzyl 12-dodecyl phosphate)-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-6-yl phosphate

Base Information

• Chemical Name: dibenzyl 2-(dibenzyl 12-dodecyl phosphate)-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-6-yl phosphate
• CAS No.: 918876-15-0
• Molecular Formula: C₅₃H₆₈O₉P₂
• Molecular Weight: 911.065
• Mol file: 918876-15-0.mol

Synonyms:

Chemical Property of dibenzyl 2-(dibenzyl 12-dodecyl phosphate)-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-6-yl phosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dibenzyl 2-(dibenzyl 12-dodecyl phosphate)-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-6-yl phosphate

There total 11 articles about dibenzyl 2-(dibenzyl 12-dodecyl phosphate)-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-6-yl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosphoric acid dibenzyl ester 12-[6-(bis-benzyloxy-phosphanyloxy)-2,5,7,8-tetramethyl-chroman-2-yl]-dodecyl ester → dibenzyl 2-(dibenzyl 12-dodecyl phosphate)-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-6-yl phosphate (918876-15-0)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1016/j.tet.2006.09.082

Reference yield:

13-methylpentadec-14-ene-1,13-diol (918876-20-7) → dibenzyl 2-(dibenzyl 12-dodecyl phosphate)-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-6-yl phosphate (918876-15-0)

Guidance literature:

Multi-step reaction with 6 steps

1.1: 76 percent / sodium hydride / tetrahydrofuran / Heating

2.1: 68 percent / HCl; zinc chloride / ethyl acetate; H₂O / 48 h / 20 °C

3.1: 92 percent / hydrogen / palladium on charcoal / ethanol / 4 h / 20 °C

4.1: ethyldiisopropylamine; 4-(dimethylamino)pyridine / CH₂Cl₂; CCl₄ / -10 °C

4.2: 78 percent / KH₂PO₄ / CH₂Cl₂; CCl₄ / 20 °C

5.1: 1H-tetrazole / CH₂Cl₂ / 3.5 h / 20 °C

6.1: 0.625 g / m-chloroperbenzoic acid / CH₂Cl₂ / 1 h / 0 °C

With 1H-tetrazole; hydrogenchloride; dmap; hydrogen; sodium hydride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; zinc(II) chloride; palladium on activated charcoal; In tetrahydrofuran; tetrachloromethane; ethanol; dichloromethane; water; ethyl acetate;

DOI:10.1016/j.tet.2006.09.082

Reference yield:

14-(tert-butyldimethylsilyloxy)tetradecan-2-one (918876-17-2) → dibenzyl 2-(dibenzyl 12-dodecyl phosphate)-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-6-yl phosphate (918876-15-0)

Guidance literature:

Multi-step reaction with 8 steps

1.1: tetrahydrofuran / 0 - 20 °C

2.1: 0.98 g / tetrabutylammonium fluoride / tetrahydrofuran / 15 h

3.1: 76 percent / sodium hydride / tetrahydrofuran / Heating

4.1: 68 percent / HCl; zinc chloride / ethyl acetate; H₂O / 48 h / 20 °C

5.1: 92 percent / hydrogen / palladium on charcoal / ethanol / 4 h / 20 °C

6.1: ethyldiisopropylamine; 4-(dimethylamino)pyridine / CH₂Cl₂; CCl₄ / -10 °C

6.2: 78 percent / KH₂PO₄ / CH₂Cl₂; CCl₄ / 20 °C

7.1: 1H-tetrazole / CH₂Cl₂ / 3.5 h / 20 °C

8.1: 0.625 g / m-chloroperbenzoic acid / CH₂Cl₂ / 1 h / 0 °C

With 1H-tetrazole; hydrogenchloride; dmap; tetrabutyl ammonium fluoride; hydrogen; sodium hydride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; zinc(II) chloride; palladium on activated charcoal; In tetrahydrofuran; tetrachloromethane; ethanol; dichloromethane; water; ethyl acetate;

DOI:10.1016/j.tet.2006.09.082

upstream raw materials:

13-methylpentadec-14-ene-1,13-diol

14-(tert-butyldimethylsilyloxy)tetradecan-2-one

15-(benzyloxy)-3-methylpentadec-1-en-3-ol

2-(12-(benzyloxy)dodecyl)-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-6-ol

Refernces