3-Fluorooxetane

Base Information

• Chemical Name: 3-Fluorooxetane
• CAS No.: 26272-86-6
• Molecular Formula: C3H5FO
• Molecular Weight: 76.0705
• Hs Code.: 2932999099
• DSSTox Substance ID: DTXSID60559408
• Wikidata: Q82442114
• Mol file: 26272-86-6.mol

Synonyms:3-fluorooxetane;26272-86-6;DTXSID60559408;AKOS015853755;AB71732;AM20020027;J-512553

Chemical Property of 3-Fluorooxetane

Chemical Property:

• Boiling Point: 35.127 °C at 760 mmHg
• PSA: 9.23000
• Density: 1.074 g/cm³
• LogP: 0.35470
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 76.032442941
• Heavy Atom Count: 5
• Complexity: 33.9

Purity/Quality:

98%min ^*data from raw suppliers

3-Fluorooxetane >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(CO1)F

Technology Process of 3-Fluorooxetane

There total 3 articles about 3-Fluorooxetane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-2-fluoro-1-propanol (26438-85-7) → fluoro-3 oxetane (26272-86-6)

Guidance literature:

With sodium hydrogencarbonate; In diethylene glycol;

Reference yield:

fluoro-2 bromo-3 propanol-1 (4161-56-2) → fluoro-3 oxetane (26272-86-6)

Guidance literature:

With sodium hydroxide; 0 degC, 15min; RT, 24h;

DOI:10.1016/S0040-4039(00)99192-5

Reference yield:

→ fluoro-3 oxetane (26272-86-6)

Guidance literature:

3-Oxetyltosylat, KF, Triethylenglykol;

DOI:10.1021/jo00951a020

upstream raw materials:

3-chloro-2-fluoro-1-propanol

fluoro-2 bromo-3 propanol-1

Downstream raw materials:

1,3-diphenoxy-2-propanol

Refernces