N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide

Base Information

• Chemical Name: N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
• CAS No.: 875337-44-3
• Molecular Formula: C26H20FN5O2S2
• Molecular Weight: 517.60
• Mol file: 875337-44-3.mol

Synonyms:MGCD-265

Chemical Property of N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide

Chemical Property:

• Appearance/Colour: White to off-white solid
• Refractive Index: 1.707
• Boiling Point: 195.7 °C at 760 mmHg
• PKA: 10.07±0.70(Predicted)
• Flash Point: 72.1 °C
• PSA: 151.93000
• Density: 1.771g/cm³
• LogP: 6.74470
• Solubility.: ≥25.9 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

Purity/Quality:

98%,99%, ^*data from raw suppliers

MGCD-265 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: MGCD-265 is a multi-targeted kinase inhibitor, which targets the c-MET, VEGFR1, VEGFR2, VEGFR3, Tie-2 and Ron receptor tyrosine kinases. MGCD-265 is a novel dual c-Met/ VEGFR2 receptor tyrosine kinase inhibitor possessing favorable pharmacokinetic profiles and showed high efficacy in vivo in several human tumor xenograft models in mice . MGCD-265 is a novel dual c-Met/ VEGFR2 receptor tyrosine kinase inhibitor possessing favorable pharmacokinetic profiles and showed high efficacy in vivo in several human tumor xenograft models in mice.