Technology Process of (4-Hexylthiophen-2-yl)boronic acid
There total 2 articles about (4-Hexylthiophen-2-yl)boronic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-hexylthiophene;
With
lithium diisopropyl amide;
In
tetrahydrofuran; n-heptane; ethylbenzene;
for 1h;
With
Trimethyl borate;
In
tetrahydrofuran; n-heptane; ethylbenzene;
at 20 ℃;
With
hydrogenchloride;
Further stages.;
DOI:10.1039/b000123f
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: Ni(dppp)Cl2 / diethyl ether
2.1: n-BuLi; i-Pr2NH / hexane; tetrahydrofuran / 3 h / -78 - 20 °C
2.2: B(OCH3)3 / hexane; tetrahydrofuran / -78 - 20 °C
2.3: HCl / tetrahydrofuran; hexane; H2O
With
n-butyllithium; diisopropylamine;
1,3-bis[(diphenylphosphino)propane]dichloronickel(II);
In
tetrahydrofuran; diethyl ether; hexane;
DOI:10.1021/jo011146z
- Guidance literature:
-
With
water; sodium hydrogencarbonate;
tetrakis(triphenylphosphine) palladium(0);
In
1,2-dimethoxyethane;
for 3h;
Heating;
DOI:10.1039/b000123f
