N-carbamoylglutamic acid

Base Information

• Chemical Name: N-carbamoylglutamic acid
• CAS No.: 40860-26-2
• Molecular Formula: C6H10N2O5
• Molecular Weight: 190.154
• DSSTox Substance ID: DTXSID90394940,DTXSID60859596
• Wikidata: Q27159095
• Metabolomics Workbench ID: 125263
• ChEMBL ID: CHEMBL1891960
• Mol file: 40860-26-2.mol

Synonyms:carbamylglutamate;N-carbamoyl-L-glutamate;N-carbamoylglutamate;N-carbamylglutamate

Chemical Property of N-carbamoylglutamic acid

Chemical Property:

• Boiling Point: 438.1 °C at 760 mmHg
• Flash Point: 218.8 °C
• PSA: 130.71000
• Density: 1.499 g/cm³
• LogP: -0.12260
• XLogP3: -2.4
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 190.05897142
• Heavy Atom Count: 13
• Complexity: 227

Purity/Quality:

99% ^*data from raw suppliers

2-(carbamoylamino)pentanedioicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CC(=O)O)C(C(=O)O)NC(=O)N

Technology Process of N-carbamoylglutamic acid

There total 3 articles about N-carbamoylglutamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

potassium cyanate (590-28-3) + Glutamic acid (617-65-2,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) → N-carbamoylglutamic acid (40860-26-2,173328-42-2)

Guidance literature:

With hydrogenchloride; In water; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1039/c8ra03761b

Reference yield:

Glutamic acid (617-65-2,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) + urea (57-13-6) → N-carbamoylglutamic acid (40860-26-2,173328-42-2)

Guidance literature:

With barium dihydroxide;

Reference yield:

D-Glutamic acid (6893-26-1,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) + urea (57-13-6) → N-carbamoylglutamic acid (40860-26-2,173328-42-2)

Guidance literature:

With barium dihydroxide; whole or partial racemized carbaminyl-glutamic acid;

upstream raw materials:

D-Glutamic acid

urea

Glutamic acid

potassium cyanate

Refernces