N-Carbamoylglutamic acid diethyl ester

Base Information

• Chemical Name: N-Carbamoylglutamic acid diethyl ester
• CAS No.: 911658-62-3
• Molecular Formula: C₁₀H₁₈N₂O₅
• Molecular Weight: 246.263
• Mol file: 911658-62-3.mol

Synonyms:N-Carbamoyl-Glutamic Acid Diethyl Ester;N-CARBAMOYLGLUTAMIC ACID DIETHYL ESTER;

Chemical Property of N-Carbamoylglutamic acid diethyl ester

Chemical Property:

• Boiling Point: 360.3±42.0 °C(Predicted)
• PKA: 12.41±0.46(Predicted)
• PSA: 107.72000
• Density: 1.169
• LogP: 1.02090

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Carbamoylglutamic acid diethyl ester

There total 3 articles about N-Carbamoylglutamic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

potassium cyanate (590-28-3) → N-carbamoyl-L-glutamic acid diethyl ester (911658-62-3)

Guidance literature:

With water;

Reference yield:

L-glutamic acid (56-86-0,21675-62-7,23009-64-5,25104-13-6,84960-48-5,25513-46-6) → N-carbamoyl-L-glutamic acid diethyl ester (911658-62-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. KOH

2: SOCl₂

With potassium hydroxide; thionyl chloride;

DOI:10.1007/BF00777980

Reference yield:

ethanol (64-17-5) + L-carglumic acid (1188-38-1) → N-carbamoyl-L-glutamic acid diethyl ester (911658-62-3)

Guidance literature:

With thionyl chloride;

DOI:10.1007/BF00777980

upstream raw materials:

ethanol

L-carglumic acid

potassium cyanate

L-glutamic acid