5-benzyl-3-(1-carboxy-2-phenylethyl)hydantoin

Base Information

• Chemical Name: 5-benzyl-3-(1-carboxy-2-phenylethyl)hydantoin
• CAS No.: 13589-09-8
• Molecular Formula: C₁₉H₁₈N₂O₄
• Molecular Weight: 338.363
• Mol file: 13589-09-8.mol

Synonyms:

Chemical Property of 5-benzyl-3-(1-carboxy-2-phenylethyl)hydantoin

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-benzyl-3-(1-carboxy-2-phenylethyl)hydantoin

There total 11 articles about 5-benzyl-3-(1-carboxy-2-phenylethyl)hydantoin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 5-benzyl-3-(1-carboxy-2-phenylethyl)hydantoin (13589-09-8)

Guidance literature:

With sodium hydroxide; at 20 ℃; higher-melting inactive form;

Reference yield:

methyl 2-bromo-3-phenylpropionate (70288-60-7,73136-26-2,124916-61-6,3196-22-3) → 5-benzyl-3-(1-carboxy-2-phenylethyl)hydantoin (13589-09-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) sodium methoxide / 1) methanol, reflux, 2 d, 2) 50 deg C, 10 d

2: 15 percent / KOH / methanol / 22 h / Ambient temperature

With potassium hydroxide; sodium methylate; In methanol;

DOI:10.1039/P19900003129

Reference yield:

5-benzyl-hydantoin (3530-82-3) → 5-benzyl-3-(1-carboxy-2-phenylethyl)hydantoin (13589-09-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) sodium methoxide / 1) methanol, reflux, 2 d, 2) 50 deg C, 10 d

2: 15 percent / KOH / methanol / 22 h / Ambient temperature

With potassium hydroxide; sodium methylate; In methanol;

DOI:10.1039/P19900003129

upstream raw materials:

N,N'-carbonyl-bis-phenylalanine

N,N'-carbonyl-bis-phenylalanine diethyl ester

methyl 2-bromo-3-phenylpropionate

5-benzyl-hydantoin

Refernces