Technology Process of 3-(Imidazo[1,2-b]pyridazin-2-yl)benzonitrile
There total 3 articles about 3-(Imidazo[1,2-b]pyridazin-2-yl)benzonitrile which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 4 - 6h;
Product distribution / selectivity;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: ethanol / 10 h / Reflux
2: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; methanol / 5 h / 20 °C
With
hydrogen;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; ethanol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: bromine / diethyl ether / 4 h / 0 - 20 °C
2: ethanol / 10 h / Reflux
3: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; methanol / 5 h / 20 °C
With
hydrogen; bromine;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; diethyl ether; ethanol;
