3,6-Dibromopyrazin-2-amine

Base Information

• Chemical Name: 3,6-Dibromopyrazin-2-amine
• CAS No.: 957230-70-5
• Molecular Formula: C₄H₃Br₂N₃
• Molecular Weight: 252.896
• Hs Code.: 2933990090
• Mol file: 957230-70-5.mol

Synonyms:3,6-dibromopyrazin-2-amine

Chemical Property of 3,6-Dibromopyrazin-2-amine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.686
• Boiling Point: 313.895 °C at 760 mmHg
• PKA: 0.05±0.10(Predicted)
• Flash Point: 143.639 °C
• PSA: 51.80000
• Density: 2.288 g/cm³
• LogP: 2.16500
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Water Solubility.: Slightly soluble in water.

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,6-Dibromopyrazin-2-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,6-Dibromopyrazin-2-amine

There total 5 articles about 3,6-Dibromopyrazin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C9H11Br2N3O2 (1082843-68-2) → 3,6-dibromopyrazin-2-amine (957230-70-5)

Guidance literature:

C₉H₁₁Br₂N₃O₂; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

With sodium hydroxide; In dichloromethane; water;

Reference yield:

3,6-dibromo-2-pyrazinamide (1301613-77-3) → 3,6-dibromopyrazin-2-amine (957230-70-5)

Guidance literature:

With bromine; potassium hydroxide; In water; at -5 - 15 ℃; for 1.08333h;

Reference yield:

3,6-dibromo-pyrazine-2-carboxylic Acid (957230-68-1) → 3,6-dibromopyrazin-2-amine (957230-70-5)

Guidance literature:

3,6-dibromo-pyrazine-2-carboxylic acid; With diphenyl phosphoryl azide; triethylamine; In tert-butyl alcohol; for 18h; Reflux;

With trifluoroacetic acid; In dichloromethane; for 0.5h;

With sodium hydroxide; In dichloromethane; water;

upstream raw materials:

3,6-dibromo-pyrazine-2-carboxylic Acid

C₉H₁₁Br₂N₃O₂

3,6-dibromo-2-pyrazinamide

Downstream raw materials:

5,8-dibromoimidazo[1,2-a]pyrazine

Refernces

• 1、 -. "FUSED PYRAZINE COMPOUNDS AS THEIR SALTS, USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES". Page/Page column 13. . Retrieved 2011/06/10.
• 2、 -. "FUSED PYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES". Page/Page column 26. . Retrieved 2009/12/05.