phenyl 2-ethylbutanoate

Base Information

• Chemical Name: phenyl 2-ethylbutanoate
• CAS No.: 54897-51-7
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.258
• Mol file: 54897-51-7.mol

Synonyms:

Chemical Property of phenyl 2-ethylbutanoate

Chemical Property:

• Boiling Point: 261.8±9.0 °C(Predicted)
• Density: 0.993±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

Phenyl2-ethylbutanoate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl 2-ethylbutanoate

There total 3 articles about phenyl 2-ethylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chlorure d'acide ethyl-2 butyrique (2736-40-5) + phenol (108-95-2,27073-41-2) → phenyl 2-ethylbutanoate (54897-51-7)

Guidance literature:

With magnesium; benzene;

DOI:10.1021/ja01147a005

Reference yield:

phenyl chloroformate (1885-14-9) + pentane (109-66-0,8031-35-4,9078-70-0) → phenyl 2-ethylbutanoate (54897-51-7) + phenyl 2-methylpentanoate

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; sodium tungstate (VI) dihydrate; phosphate potassium salt; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; 4,4'-di-tert-butyl-2,2'-bipyridine; In benzene; at 34 ℃; for 48h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1021/jacs.8b09191

Reference yield:

2-Ethylbutanoic acid (88-09-5) → phenyl 2-ethylbutanoate (54897-51-7)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 3 h / 0 °C / Inert atmosphere

2: pyridine / dichloromethane / 20 °C / Inert atmosphere

With pyridine; oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane;

DOI:10.1021/jacs.8b09191

upstream raw materials:

chlorure d'acide ethyl-2 butyrique

phenol

2-Ethylbutanoic acid

phenyl chloroformate

Downstream raw materials:

3,7-diethyl-5-methyl-4,6-nonanedione

3-ethyl-undecane-4,6-dione

Refernces