Ethylene glycol bis(1,1,2,2-tetrafluoroethyl) ether

Base Information

• Chemical Name: Ethylene glycol bis(1,1,2,2-tetrafluoroethyl) ether
• CAS No.: 358-39-4
• Molecular Formula: C6H6F8O2
• Molecular Weight: 262.10
• Hs Code.: 2909199090
• European Community (EC) Number: 879-259-4
• DSSTox Substance ID: DTXSID80569266
• Wikidata: Q72447009
• Mol file: 358-39-4.mol

Synonyms:Ethylene glycol bis(1,1,2,2-tetrafluoroethyl) ether;1,1,2,2-tetrafluoro-1-[2-(1,1,2,2-tetrafluoroethoxy)ethoxy]ethane;

Chemical Property of Ethylene glycol bis(1,1,2,2-tetrafluoroethyl) ether

Chemical Property:

• Refractive Index: 1.3202
• Boiling Point: 140.993 °C at 760 mmHg
• Flash Point: 44.933 °C
• PSA: 18.46000
• Density: 1.419 g/cm³
• LogP: 2.73540
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 7
• Exact Mass: 262.02400473
• Heavy Atom Count: 16
• Complexity: 185

Purity/Quality:

99% ^*data from raw suppliers

1,2-(1,1,2,2-Tetrafluoroethoxy)ethane 99% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(COC(C(F)F)(F)F)OC(C(F)F)(F)F

Technology Process of Ethylene glycol bis(1,1,2,2-tetrafluoroethyl) ether

There total 3 articles about Ethylene glycol bis(1,1,2,2-tetrafluoroethyl) ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

polytetrafluoroethylene (116-14-3,82785-14-6) + 1,2-bis(trifluoroacetyl)ethane (2613-44-7) → 1,2-bis-(1,1,2,2-tetrafluoro-ethoxy)-ethane (358-39-4)

Guidance literature:

With sodium hydroxide; In water; at 95 ℃; for 1h; under 2250.23 Torr; Inert atmosphere;

Reference yield: 33.0%

polytetrafluoroethylene (116-14-3,82785-14-6) + ethylene glycol (107-21-1) → 1,2-bis-(1,1,2,2-tetrafluoro-ethoxy)-ethane (358-39-4)

Guidance literature:

With potassium hydroxide; In N,N-dimethyl-formamide; -78 to 30...80 deg C;

DOI:10.1016/S0022-1139(00)80963-X

Reference yield:

polytetrafluoroethylene (116-14-3,82785-14-6) + ethylene glycol (107-21-1) → 2-(1,1,2,2-tetrafluoro-ethoxy)-ethanol (428-57-9) + 1,2-bis-(1,1,2,2-tetrafluoro-ethoxy)-ethane (358-39-4)

Guidance literature:

With diethyl ether; sodium; at 75 ℃;

upstream raw materials:

polytetrafluoroethylene

ethylene glycol

1,2-bis(trifluoroacetyl)ethane

Refernces

• 1、 Sievert, Allen C.,Tong, Walter R.,Nappa, Mario J.. "SYNTHESIS OF PERFLUORINATED ETHERS BY AN IMPROVED SOLUTION PHASE DIRECT FLUORINATION PROCESS". . p. 397 - 418. Retrieved 2007/10/02.