(1R,2R)-1,2-BIS(2,4,6-TRIMETHYLPHENYL)ETHYLENEDIAMINE

Base Information

• Chemical Name: (1R,2R)-1,2-BIS(2,4,6-TRIMETHYLPHENYL)ETHYLENEDIAMINE
• CAS No.: 425615-42-5
• Molecular Formula: C20H28N2
• Molecular Weight: 296.45
• Hs Code.: 2921290000
• Mol file: 425615-42-5.mol

Synonyms:(1R,2R)-1,2-DIMESITYLETHYLENEDIAMINE;(1R,2R)-1,2-DIAMINO-1,2-DIMESITYLETHANE;(R,R)-1,2-Bis(2,4,6-trimethylphenyl)-1,2-ethanediamine dihydrochloride;

Chemical Property of (1R,2R)-1,2-BIS(2,4,6-TRIMETHYLPHENYL)ETHYLENEDIAMINE

Chemical Property:

• Vapor Pressure: 2.37E-08mmHg at 25°C
• Refractive Index: 1.579
• Boiling Point: 451.7 °C at 760 mmHg
• Flash Point: 272.3 °C
• PSA: 52.04000
• Density: 1.024 g/cm³
• LogP: 5.63740

Purity/Quality:

98% ^*data from raw suppliers

(1R,2R)-1,2-Bis(2,4,6-trimethylphenyl)ethylenediamine ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

Useful:

Technology Process of (1R,2R)-1,2-BIS(2,4,6-TRIMETHYLPHENYL)ETHYLENEDIAMINE

There total 1 articles about (1R,2R)-1,2-BIS(2,4,6-TRIMETHYLPHENYL)ETHYLENEDIAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[1-(2,4,6-Trimethyl-phenyl)-meth-(E)-ylidene]-trimethylsilanyl-amine → (1S,2S)-1,2-di(2,4,6-trimethylphenyl)-1,2-ethanediamine (186769-18-6) + (R,R)-1,2-bis(2,4,6-trimethylphenyl)-1,2-ethanediamine (425615-42-5,186769-18-6)

Guidance literature:

With tetrachlorobis(tetrahydrofuran)niobium(IV); In 1,2-dimethoxyethane; resolution of racemate;

DOI:10.1021/ol0266018

Reference yield: 95.0%

(R,R)-1,2-bis(2,4,6-trimethylphenyl)-1,2-ethanediamine (425615-42-5,186769-18-6) + o-phthalic dicarboxaldehyde (643-79-8) → (2R,3R)-2,3-dimesityl-3,5-dihydro-2H-imidazo[2,1-a]isoindole (1268872-88-3)

Guidance literature:

In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1016/j.tetasy.2010.12.002

Reference yield: 90.0%

(R,R)-1,2-bis(2,4,6-trimethylphenyl)-1,2-ethanediamine (425615-42-5,186769-18-6) + bromocyane (506-68-3) → (4R,5R)-4,5-dimesitylimidazolidin-2-imine (1130601-48-7)

Guidance literature:

In acetonitrile; for 48h; Inert atmosphere; Reflux;

DOI:10.1016/j.tetlet.2008.12.058

Downstream raw materials:

(4R,5R)-4,5-dimesitylimidazolidin-2-imine

(2R,3R)-2,3-dimesityl-3,5-dihydro-2H-imidazo[2,1-a]isoindole

Refernces