Technology Process of 3-(4,6-dimethyl-3,5-di((E)-prop-1-enyl)pyridin-2-yl)propan-1-ol hydrochloride
There total 7 articles about 3-(4,6-dimethyl-3,5-di((E)-prop-1-enyl)pyridin-2-yl)propan-1-ol hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; water;
In
ethanol;
for 3h;
Reflux;
DOI:10.1021/jo2013669
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dibromoborane dimethylsulfide / dichloromethane / 4 h / 0 - 20 °C
1.2: 0.25 h / 0 °C
2.1: palladium diacetate; sodium carbonate; triphenylphosphine / ethanol; water; toluene / 6 h / Inert atmosphere; Reflux
3.1: hydrogenchloride; water / ethanol / 3 h / Reflux
With
hydrogenchloride; dibromoborane dimethylsulfide; water; palladium diacetate; sodium carbonate; triphenylphosphine;
In
ethanol; dichloromethane; water; toluene;
2.1: Suzuki coupling;
DOI:10.1021/jo2013669
- Guidance literature:
-
Multi-step reaction with 3 steps
1: platinum(IV) oxide; hydrogen; triethylamine / ethanol / 1 h
2: palladium diacetate; sodium carbonate; triphenylphosphine / ethanol; water; toluene / 6 h / Inert atmosphere; Reflux
3: hydrogenchloride; water / ethanol / 3 h / Reflux
With
hydrogenchloride; platinum(IV) oxide; water; hydrogen; palladium diacetate; sodium carbonate; triethylamine; triphenylphosphine;
In
ethanol; water; toluene;
2: Suzuki coupling;
DOI:10.1021/jo2013669