Benzoic acid, 2-aMino-4-Methoxy-5-[3-(4-Morpholinyl)propoxy]-, Methyl ester

Base Information Edit

Chemical Name:Benzoic acid, 2-aMino-4-Methoxy-5-[3-(4-Morpholinyl)propoxy]-, Methyl ester
CAS No.:214472-41-0
Molecular Formula:C16H24N2O5
Molecular Weight:324.377
Hs Code.:
Mol file:214472-41-0.mol

Synonyms:methyl 2-amino-4-methoxy-5-(3-morpholin-4-yl-propoxy)benzoate; Benzoic acid, 2-amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]-, methyl ester; methyl 2-amino-4-methoxy-5-(3-morpholinopropoxy)benzoate; 2-amino-4-methoxy-5-(3-morpholin-4-ylpropoxy)benzoic acid methyl ester; methyl 2-amino-4-methoxy-3-(3-morpholinopropoxy)benzoate;

Suppliers and Price of Benzoic acid, 2-aMino-4-Methoxy-5-[3-(4-Morpholinyl)propoxy]-, Methyl ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 10 raw suppliers

Chemical Property of Benzoic acid, 2-aMino-4-Methoxy-5-[3-(4-Morpholinyl)propoxy]-, Methyl ester Edit

Chemical Property:

PSA：83.25000
LogP:1.68420

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 2-aMino-4-Methoxy-5-[3-(4-Morpholinyl)propoxy]-, Methyl ester

There total 7 articles about Benzoic acid, 2-aMino-4-Methoxy-5-[3-(4-Morpholinyl)propoxy]-, Methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

: 214472-37-4
4-methoxy-5-(3-morpholinylpropoxy)-2-nitrobenzoic acid methyl ester

: 214472-41-0
methyl 5-(3-morpholinopropoxy)-2-amino-4-methoxy-benzoate

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethyl acetate; for 3h; under 3345.86 Torr;

Reference yield:

: 6702-50-7
3-hydroxy-4-methoxybenzoate

: 214472-41-0
methyl 5-(3-morpholinopropoxy)-2-amino-4-methoxy-benzoate

Guidance literature:: Multi-step reaction with 4 steps

1: 76 percent / potassium carbonate / acetone / 24 h / Heating

2: 82 percent / nitric acid; trifluoroacetic acid / CH₂Cl₂ / 2 h / 20 °C

3: 60 percent / 1 h / 100 °C

4: hydrogen / palladium on activated carbon / methanol

With hydrogen; nitric acid; potassium carbonate; trifluoroacetic acid; palladium on activated charcoal; In methanol; dichloromethane; acetone;
DOI:10.1002/jlcr.998

Reference yield:

: 645-08-9,74309-78-7
Isovanillic acid

: 214472-41-0
methyl 5-(3-morpholinopropoxy)-2-amino-4-methoxy-benzoate

Guidance literature:: Multi-step reaction with 4 steps

1: 99 percent / H₂SO₄ / Heating

2: 95 percent / tri-n-butyl ammonium iodide; K₂CO₃ / butan-2-one / Heating

3: 88 percent / HNO₃; AcOH

4: 74 percent / H₂ / Pd/C / ethanol; ethyl acetate

With sulfuric acid; hydrogen; nitric acid; tri-n-butylammonium iodide; potassium carbonate; acetic acid; palladium on activated charcoal; In ethanol; ethyl acetate; butanone; 1: Fisher esterification;
DOI:10.1016/S0960-894X(02)00598-X