2-isonicotinoyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

Base Information Edit

Chemical Name:2-isonicotinoyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
CAS No.:923571-15-7
Molecular Formula:C17H15NO4
Molecular Weight:297.31
Hs Code.:
Mol file:923571-15-7.mol

Synonyms:5,6-dimethoxy-2-(di-n-propylamino)indan;5,6-dimethoxy-n,n-dipropylindan-2-amine;Lopac-U-116;5,6-dimethoxy-2-(pyridine-4-carbonyl)indan-1-one;

Suppliers and Price of 2-isonicotinoyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,3-Dihydro-5,6-dimethoxy-2-(4-pyridinylcarbonyl)-1H-inden-1-one
10mg
$ 1320.00

Total 9 raw suppliers

Chemical Property of 2-isonicotinoyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one Edit

Chemical Property:

Boiling Point:510.6±50.0 °C(Predicted)
PKA:7.08±0.20(Predicted)
PSA：65.49000
Density:1.274±0.06 g/cm3(Predicted)
LogP:2.33670

Purity/Quality:

99.0% Min ^*data from raw suppliers

2,3-Dihydro-5,6-dimethoxy-2-(4-pyridinylcarbonyl)-1H-inden-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2,3-Dihydro-5,6-dimethoxy-2-(4-pyridinylcarbonyl)-1H-inden-1-one is an impurity in the synthesis of Donezepil (D531750), A nootropic. An inhibitor of acetylcholinesterase.

Technology Process of 2-isonicotinoyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

There total 2 articles about 2-isonicotinoyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 2459-09-8
4-pyridinecarboxylic acid, methyl ester

: 2107-69-9
5,6-dimethoxy-1-indanone

: 923571-15-7
5,6-dimethoxy-2-(pyridine-4-carbonyl)indan-1-one

Guidance literature:: 4-pyridinecarboxylic acid, methyl ester; 5,6-dimethoxy-1-indanone; In methanol; toluene; at 20 ℃; for 0.166667h;

With sodium methylate; In methanol; toluene; at 20 - 103 ℃; for 2.5h; Product distribution / selectivity;