2,3-epoxy-1-2'-methoxymethoxyphenyl-3-phenylpropanol

Base Information

• Chemical Name: 2,3-epoxy-1-2'-methoxymethoxyphenyl-3-phenylpropanol
• CAS No.: 91299-68-2
• Molecular Formula: C₁₇H₁₈O₄
• Molecular Weight: 286.328
• Mol file: 91299-68-2.mol

Synonyms:

Chemical Property of 2,3-epoxy-1-2'-methoxymethoxyphenyl-3-phenylpropanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-epoxy-1-2'-methoxymethoxyphenyl-3-phenylpropanol

There total 2 articles about 2,3-epoxy-1-2'-methoxymethoxyphenyl-3-phenylpropanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

2,3-epoxy-1-2'-methoxymethoxyphenyl-3-phenylpropanone (95280-66-3) → 2,3-epoxy-1-2'-methoxymethoxyphenyl-3-phenylpropanol (91299-68-2,91383-17-4,96790-78-2,96790-79-3)

Guidance literature:

With sodium tetrahydroborate; In methanol; at -20 ℃; for 2h;

Reference yield:

2'-O-methoxymethylchalcone (40524-63-8) → 2,3-epoxy-1-2'-methoxymethoxyphenyl-3-phenylpropanol (91299-68-2,91383-17-4,96790-78-2,96790-79-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 41 percent / BQdC, 2N NaOH, 30percent H₂O₂ / toluene; H₂O / 72 h / Ambient temperature

2: 69 percent / NaBH₄ / methanol / 2 h / -20 °C

With sodium hydroxide; sodium tetrahydroborate; dihydrogen peroxide; In methanol; water; toluene;

Reference yield: 68.0%

2,3-epoxy-1-2'-methoxymethoxyphenyl-3-phenylpropanol (91299-68-2,91383-17-4,96790-78-2,96790-79-3) → flavan-3,4-diol (1086-73-3,5023-02-9,6059-69-4,21391-59-3,55568-95-1,55568-99-5,91383-18-5,91383-19-6,96790-75-9,96790-80-6)

Guidance literature:

With hydrogenchloride; In methanol; for 0.666667h; Ambient temperature;

upstream raw materials:

2,3-epoxy-1-2'-methoxymethoxyphenyl-3-phenylpropanone

2'-O-methoxymethylchalcone

Downstream raw materials:

flavan-3,4-diol

C₂₉H₂₂O₅

Refernces