N3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine

Base Information

• Chemical Name: N3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine
• CAS No.: 522629-08-9
• Molecular Formula: C11H9FN6
• Molecular Weight: 244.2278
• Hs Code.: 2933599590
• European Community (EC) Number: 637-056-6
• ChEMBL ID: CHEMBL1240885
• DSSTox Substance ID: DTXSID50469941
• Nikkaji Number: J2.094.222C
• NSC Number: 741567
• Pharos Ligand ID: QTJH18H5WGUC
• Wikidata: Q27087429
• Mol file: 522629-08-9.mol

Synonyms:CGP 57380;CGP-57380;CGP57380

Chemical Property of N3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.809
• Boiling Point: 541.635°C at 760 mmHg
• Flash Point: 281.371°C
• PSA: 92.51000
• Density: 1.585g/cm³
• LogP: 2.47200
• Storage Temp.: 2-8°C
• Solubility.: DMSO: soluble10mg/mL, clear
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 244.08727247
• Heavy Atom Count: 18
• Complexity: 283

Purity/Quality:

99% ^*data from raw suppliers

CGP 57380 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F
• Uses: CGP 57380 has been used: as a mitogen-activated protein kinase-interacting kinase 1 (MNK1) inhibitor to investigate the role of Mnk1 on eukaryotic translation initiation factor 4F (eIF4F) assembly and Newcastle disease virus (NDV) replication in HeLa cellsas an MNK1 inhibitor to block eIF4 complex to evaluate the contribution of interferon (IFN-γ) translation during m157- transgenic (Tg) stimulationas a β-catenin nuclear translocation inhibitor to analyze its effects on cytoplasmic and nuclear fractions of cells