PIK-294

Base Information

• Chemical Name: PIK-294
• CAS No.: 900185-02-6
• Molecular Formula: C28H23N7O2
• Molecular Weight: 489.536
• Mol file: 900185-02-6.mol

Synonyms:PIK-294;2-[[4-Amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone

Chemical Property of PIK-294

Chemical Property:

• Boiling Point: 790.4±70.0 °C(Predicted)
• PKA: 8.95±0.10(Predicted)
• PSA: 124.74000
• Density: 1.43
• LogP: 4.72650
• Storage Temp.: -20°C
• Solubility.: ≥24.5 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH

Purity/Quality:

98%,99%, ^*data from raw suppliers

PIK-294 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: PIK-294 is a highly selective p110δ inhibitor with IC50 of 10 nM, 1000-, 49- and 16-fold less potent to PI3Kα/β/γ, respectively.
• Uses: PIK-294 is a derivative of PIK-293 (P437700) and a highly selective inhibitor of p110δ which is an isoform of phosphoinositide 3-kinase (PI3K).