ALPHA-METHYLBENZYL ALCOHOL

Base Information

• Chemical Name: ALPHA-METHYLBENZYL ALCOHOL
• CAS No.: 13323-81-4
• Molecular Formula: C₈H₁₀O
• Molecular Weight: 122.167
• Mol file: 13323-81-4.mol

Synonyms:1-phenylethanol;ALPHA-METHYLBENZYL ALCOHOL;(+/-)-1-PHENYLETHANOL;1-PHENYLETHYL ALCOHOL;A-METHYLBENZYL ALCOHOL;AURORA KA-7014;DL-1-Phenethylalcohol;DL-1-PHENYLETHYL ALCOHOL;DL-2-METHYL PHENYL METHANOL;DL-ALPHA-METHYLBENZYL ALCOHOL;DL-ALPHA-METHYLPHENYLCARBINOL;DL-A-METHYLBENZYL ALCOHOL;DL-METHYLPHENYLCARBINOL;DL-PHENYLMETHYLCARBINOL;DL-SEC-PHENETHYL ALCOHOL;dl-sec-phenylethanol;DL-STYRALYL ALCOHOL;FEMA 2685;

Chemical Property of ALPHA-METHYLBENZYL ALCOHOL

Chemical Property:

• Vapor Pressure: 0.1 mm Hg ( 20 °C)
• Melting Point: 19-20 °C(lit.)
• Refractive Index: n20/D 1.527(lit.)
• Boiling Point: 204 °C745 mm Hg(lit.)
• Flash Point: 185 °F
• PSA: 20.23000
• Density: 1.012 g/mL at 25 °C(lit.)
• LogP: 1.73990

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-38-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ALPHA-METHYLBENZYL ALCOHOL

There total 971 articles about ALPHA-METHYLBENZYL ALCOHOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

triethyl(1-phenylethoxy)silane (112473-30-0,18442-52-9) → triethylsilyl fluoride (358-43-0) + 1-Phenylethanol (98-85-1,13323-81-4)

Guidance literature:

With methylammmonium fluoride; In methanol; at 20 ℃; for 24h;

Reference yield: 100.0%

1-phenyl-2-(phenylseleno)-1-ethenol p-toluenesulfonate (128736-56-1) → 1-Phenylethanol (98-85-1,13323-81-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 24h;

DOI:10.1021/jo00008a039

Reference yield: 98.0%

2-(1-phenylethoxy)-tetrahydro-2H-pyran (105966-39-0) → 1-Phenylethanol (98-85-1,13323-81-4)

Guidance literature:

With bismuth(lll) trifluoromethanesulfonate; In methanol; for 0.05h; Heating;

DOI:10.1081/SCC-120004252

upstream raw materials:

styrene

styrene oxide

tetrahydro-2-phenylfuran

hexane

Downstream raw materials:

1-ethoxy-1-phenylethane

N-(1-phenylethyl)benzamide

(1-chloroethyl)benzene

styrene

Refernces

• 1、 Li, Yuan,Jie, Shanshan,Li, Kun,Liu, Zhigang. "Synthesis of efficient Co and N co-doped carbon catalysts with high surface areas for selective oxidation of ethylbenzene". . p. 12677 - 12683. Retrieved 2018.
• 2、 Wiegrebe. "Conversion of 1-benzylisoquinolines into berbinium salts. 2. Determination of the structure of an "Alteupaverin" derivative C21H17NO5". . . Retrieved 1967.
• 3、 Martin-Matute, Belen,Aberg, Jenny B.,Edin, Michaela,Baeckvall, Jan-E.. "Racemization of secondary alcohols catalyzed by cyclopentadienyl-ruthenium complexes: Evidence for an alkoxide pathway by fast β-hydride elimination-readdition". . p. 6063 - 6072. Retrieved 2007.
• 4、 Laxmi, Y. R. Santosh,Baeckvall, Jan-E.. "Mechanistic studies on ruthenium-catalyzed hydrogen transfer reactions". . p. 611 - 612. Retrieved 2000.
• 5、 Komiya, Naruyoshi,Naota, Takeshi,Murahashi, Shun-Ichi. "Aerobic oxidation of alkanes in the presence of acetaldehyde catalysed by Copper-crown ether". . p. 1633 - 1636. Retrieved 1996.
• 6、 Hayakawa, Shohei,Matsumura, Hirotoshi,Nakamura, Nobuhumi,Yohda, Masafumi,Ohno, Hiroyuki. "Identification of the rate-limiting step of the peroxygenase reactions catalyzed by the thermophilic cytochrome P450 from Sulfolobus tokodaii strain 7". . p. 1409 - 1416. Retrieved 2014.
• 7、 Sato,Yoshiie. "-". . p. 415. Retrieved 1976.
• 8、 Dobras, Gabriela,Sitko, Magdalena,Petroselli, Manuel,Caruso, Manfredi,Cametti, Massimo,Punta, Carlo,Orlińska, Beata. "Solvent-Free Aerobic Oxidation of Ethylbenzene Promoted by NHPI/Co(II) Catalytic System: The Key Role of Ionic Liquids". . p. 259 - 266. Retrieved 2020.
• 9、 Hamnevik, Emil,Blikstad, Cecilia,Norrehed, Sara,Widersten, Mikael. "Kinetic characterization of Rhodococcus ruber DSM 44541 alcohol dehydrogenase A". . p. 68 - 78. Retrieved 2014.
• 10、 Merritt, Margaret V.,Chang, I-Wen,Flannery, Clare A.,Hsieh, Show-Jon,Lee, Karl,Yung, Jennifer. "Micelle-induced changes in the solvation of carbocations: Effect of sodium dodecyl sulfate micelles on the enantiomer-specific oxygen exchange reactions of 1-phenyl-1-ethanol and 1-phenyl-1-butanol". . p. 9791 - 9799. Retrieved 1995.