5-Methyl-3-nitro-2-pyridinecarbonitrile

Base Information

• Chemical Name: 5-Methyl-3-nitro-2-pyridinecarbonitrile
• CAS No.: 1089330-68-6
• Molecular Formula: C7H5N3O2
• Molecular Weight: 163.13
• Hs Code.: 2933399090
• Mol file: 1089330-68-6.mol

Synonyms:5-methyl-3-nitropyridine-2-carbonitrile

Chemical Property of 5-Methyl-3-nitro-2-pyridinecarbonitrile

Chemical Property:

• Boiling Point: 378.2 °C at 760 mmHg
• Flash Point: 182.5 °C
• PSA: 82.50000
• Density: 1.34 g/cm³
• LogP: 1.69308
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-Methyl-3-nitropicolinonitrile ^*data from reagent suppliers

Safty Information:

• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Methyl-3-nitro-2-pyridinecarbonitrile

There total 1 articles about 5-Methyl-3-nitro-2-pyridinecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-bromo-5-methyl-3-nitropyridine (23056-46-4) + copper(I) cyanide (544-92-3) → 2-cyano-5-methyl-3-nitropyridine (1089330-68-6)

Guidance literature:

In N,N-dimethyl-formamide; at 70 ℃; for 1.5h;

Reference yield:

2-cyano-5-methyl-3-nitropyridine (1089330-68-6) → 3-amino-5-methylpyridine-2-carbonitrile (1001635-30-8) + 3-amino-5-methyl-pyridine-2-carboxylic acid amide (1208081-47-3)

Guidance literature:

With iron; acetic acid; at 60 - 80 ℃; for 4h;

upstream raw materials:

2-bromo-5-methyl-3-nitropyridine

copper(I) cyanide

Downstream raw materials:

3-amino-5-methylpyridine-2-carbonitrile

3-amino-5-methyl-pyridine-2-carboxylic acid amide

Refernces