2-Amino-3,4-dimethoxybenzoic acid

Base Information

• Chemical Name: 2-Amino-3,4-dimethoxybenzoic acid
• CAS No.: 5701-87-1
• Molecular Formula: C9H11NO4
• Molecular Weight: 197.191
• Hs Code.: 2922509090
• Mol file: 5701-87-1.mol

Synonyms:2-Amino-3,4-dimethoxybenzoic acid;

Chemical Property of 2-Amino-3,4-dimethoxybenzoic acid

Chemical Property:

• Boiling Point: 344.906 °C at 760 mmHg
• Flash Point: 162.393 °C
• PSA: 81.78000
• Density: 1.295 g/cm³
• LogP: 1.56540
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-3,4-dimethoxybenzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-Amino-3,4-dimethoxybenzoic Acid is a useful building block.

Technology Process of 2-Amino-3,4-dimethoxybenzoic acid

There total 12 articles about 2-Amino-3,4-dimethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

3,4-Dimethoxy-2-nitro-benzoic acid (79025-28-8) → 3,4-dimethoxyanthranilic acid (5701-87-1)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In ethanol; for 16h; under 2585.81 Torr;

DOI:10.1039/c4md00113c

Reference yield:

3,4-Dimethoxy-2-nitro-benzoic acid (79025-28-8) → 3,4-dimethoxyanthranilic acid (5701-87-1) + anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4)

Guidance literature:

In ammonium hydroxide;

Reference yield:

2-nitroveratraldehyde (55149-84-3) → 3,4-dimethoxyanthranilic acid (5701-87-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / KMnO₄

2: 82 percent / FeSO₄, NH₃

With potassium permanganate; ammonia; iron(II) sulfate;

upstream raw materials:

3,4-Dimethoxy-2-nitro-benzoic acid

3,4-dimethoxyphthalimide

4-(3,4-dimethoxy-2-nitro-benzylidene)-2-phenyl-4H-oxazol-5-one

2-nitroveratraldehyde

Downstream raw materials:

2-amino-3,4-dimethoxy-benzoic acid methyl ester

7,8-dimethoxyquinazolin-4(3H)-one

methyl 2-bromo-3,4-dimetoxybenzoate

2-acetylamino-3,4-dimethoxy-benzoic acid

Refernces

• 1、 -. "Multisubstituted 1-hydroxy-9-acridones with anticancer activity". . . Retrieved 2008/06/13.
• 2、 -. "Alkoxy-substituted-6-chloro-quinazoline-2,4-diones". . . Retrieved 2008/06/13.