BenzenaMine, 3-broMo-N-Methyl-2-nitro-

Base Information

• Chemical Name: BenzenaMine, 3-broMo-N-Methyl-2-nitro-
• CAS No.: 1150617-53-0
• Molecular Formula: C7H7BrN2O2
• Molecular Weight: 231.049
• Hs Code.: 2921420090
• Mol file: 1150617-53-0.mol

Synonyms:3-Bromo-N-methyl-2-nitro-aniline;

Chemical Property of BenzenaMine, 3-broMo-N-Methyl-2-nitro-

Chemical Property:

• Boiling Point: 298.115 °C at 760 mmHg
• Flash Point: 134.096 °C
• PSA: 57.85000
• Density: 1.688 g/cm³
• LogP: 2.99520

Purity/Quality:

99% ^*data from raw suppliers

3-Bromo-N-methyl-2-nitroaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BenzenaMine, 3-broMo-N-Methyl-2-nitro-

There total 1 articles about BenzenaMine, 3-broMo-N-Methyl-2-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

methylamine (74-89-5) + 2?bromo?6?fluoronitrobenzene (886762-70-5) → 3-bromo-N-methyl-2-nitrobenzenamine (1150617-53-0)

Guidance literature:

In ethanol;

Reference yield: 86.0%

3-bromo-N-methyl-2-nitrobenzenamine (1150617-53-0) → 3-bromo-N1-methylbenzene-1,2-diamine dihydrochloride

Guidance literature:

3-bromo-N-methyl-2-nitrobenzenamine; With iron(III) chloride hexahydrate; hydrazine hydrate; In ethanol; water; at 100 ℃; for 0.666667h;

With hydrogenchloride; In ethyl acetate;

DOI:10.1016/j.bmc.2015.04.052

Reference yield: 80.0%

3-bromo-N-methyl-2-nitrobenzenamine (1150617-53-0) → 3-bromo-N1-methylbenzene-1,2-diamine (1150617-55-2)

Guidance literature:

With iron; acetic acid; at 60 ℃; for 1h;

upstream raw materials:

methylamine

2?bromo?6?fluoronitrobenzene

Downstream raw materials:

3-bromo-N¹-methylbenzene-1,2-diamine

[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]-[2-(3-methoxyphenyl)-1-methyl-1H-benzoimidazol-4-yl]amine

(2-isobutyl-1-methyl-1H-benzoimidazol-4-yl)-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]amine

[2-(4-fluorophenyl)-1-methyl-1H-benzoimidazol-4-yl]-[6-methoxy-5-(4-methylimidazol-1-yl)pyridin-2-yl]amine

Refernces

• 1、 -. "METALLO-BETA-LACTAMASE INHIBITORS". Page/Page column 78. . Retrieved 2017/04/04.
• 2、 -. "NOVEL SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS GAMMA SECRETASE MODULATORS". Page/Page column 67. . Retrieved 2010/08/18.