2,6-DIFORMYLPHENOL

Base Information

• Chemical Name: 2,6-DIFORMYLPHENOL
• CAS No.: 3328-69-6
• Molecular Formula: C8H6O3
• Molecular Weight: 150.134
• Hs Code.: 2912499000
• Mol file: 3328-69-6.mol

Synonyms:Isophthalaldehyde,2-hydroxy- (7CI,8CI);2,6-Diformylphenol;2-Hydroxy-1,3-benzenedicarboxaldehyde;2-Hydroxyisophthalaldehyde;NSC 403253;

Chemical Property of 2,6-DIFORMYLPHENOL

Chemical Property:

• Vapor Pressure: 0.0827mmHg at 25°C
• Melting Point: 124 °C
• Refractive Index: 1.672
• Boiling Point: 219°C at 760 mmHg
• PKA: 6.38±0.10(Predicted)
• Flash Point: 100.5°C
• PSA: 54.37000
• Density: 1.35g/cm³
• LogP: 1.01720
• Storage Temp.: Refrigerator
• Solubility.: soluble in Methanol

Purity/Quality:

98%, ^*data from raw suppliers

2,6-Diformylphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-DIFORMYLPHENOL

There total 17 articles about 2,6-DIFORMYLPHENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

Cu2(C6H3(O)(CHNCH2CH2C5H4N)2)OH(2+)*2BF4(1-)=[Cu2(C6H3(O)(CHNCH2CH2C5H4N)2)OH](BF4)2 → 2-hydroxy-isophthalaldehyde (3328-69-6)

Guidance literature:

With hydrogenchloride; water; Hydrolysis of Cu-complex, using aq. HCl.;

Reference yield: 72.0%

2,6-(α,α,α',α'-tetrabromo)dimethylacetoxybenzene (176243-28-0) → 2-hydroxy-isophthalaldehyde (3328-69-6)

Guidance literature:

With sodium acetate; In acetic acid; for 48h; Heating;

DOI:10.1016/S0040-4039(97)00558-3

Reference yield: 65.1%

trifluoroacetic acid (76-05-1) + phenol (108-95-2,27073-41-2) → 2-hydroxy-isophthalaldehyde (3328-69-6)

Guidance literature:

With hexamethylenetetramine; Reflux;

upstream raw materials:

3-formylsalicylic acid

Isophthalaldehyde

cyclohexenone

formic acid ethyl ester

Downstream raw materials:

2,6-bis-1-hydroxybenzene

2?hydroxy?5?nitroisophthalaldehyde

2-hydroxyisophthalic acid

2,6-diformyl-4-iodophenol

Refernces

• 1、 Casella, Luigi,Gullotti, Michele,Pallanza, Gianfranco,Rigoni, Luigi. "Synthesis and Reactivity of a Family of Copper Monooxygenase Model Systems". . p. 4221 - 4227. Retrieved 1988.
• 2、 -. "Method for preparing kit for detecting cysteine". Paragraph 0043; 0045; 0046; 0047; 0048; 0049; 0050. . Retrieved 2018/07/15.
• 3、 -. "Kit for detecting cysteine". Paragraph 0043-0050. . Retrieved 2018/09/08.