Aceclofenac Benzyl Ester

Base Information

• Chemical Name: Aceclofenac Benzyl Ester
• CAS No.: 100499-89-6
• Molecular Formula: C23H19Cl2NO4
• Molecular Weight: 444.314
• Mol file: 100499-89-6.mol

Synonyms:(2-Benzyloxy-2-oxo-ethyl) 2-[2-(2,6-dichloroanilino)phenyl]acetate;2-(Benzyloxy)-2-oxoethyl {2-[(2,6-dichlorophenyl)amino]phenyl}acetate;Aceclofenac benzyl ester;

Chemical Property of Aceclofenac Benzyl Ester

Chemical Property:

• Vapor Pressure: 1.06E-11mmHg at 25°C
• Refractive Index: 1.628
• Boiling Point: 539.3 °C at 760 mmHg
• PKA: -2.85±0.50(Predicted)
• Flash Point: 280 °C
• PSA: 64.63000
• Density: 1.348 g/cm³
• LogP: 5.63910

Purity/Quality:

99.9% ^*data from raw suppliers

AceclofenacBenzylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A 2-[(2,6-dichlorophenyl)amino]phenylacetoxyacetyl derivative

Technology Process of Aceclofenac Benzyl Ester

There total 1 articles about Aceclofenac Benzyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Benzyl chloroacetate (140-18-1) + diclofenac sodium (15307-79-6) → aceclofenac benzyl ester (100499-89-6)

Guidance literature:

In N,N-dimethyl-formamide;

DOI:10.1007/BF01199535

Reference yield:

aceclofenac benzyl ester (100499-89-6) → aceclofenac (89796-99-6)

Guidance literature:

With hydrogen; palladium on activated charcoal;

DOI:10.1007/BF01199535

upstream raw materials:

Benzyl chloroacetate

diclofenac sodium

Downstream raw materials:

aceclofenac

Refernces