4-methyl-2-(morpholinomethyl)-6-allylphenol

Base Information

• Chemical Name: 4-methyl-2-(morpholinomethyl)-6-allylphenol
• CAS No.: 114035-62-0
• Molecular Formula: C₁₅H₂₁NO₂
• Molecular Weight: 247.337
• Mol file: 114035-62-0.mol

Synonyms:

Chemical Property of 4-methyl-2-(morpholinomethyl)-6-allylphenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methyl-2-(morpholinomethyl)-6-allylphenol

There total 3 articles about 4-methyl-2-(morpholinomethyl)-6-allylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.2%

morpholine (110-91-8,99108-56-2) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-allyl-4-methylphenol (6628-06-4) → 4-methyl-2-(morpholinomethyl)-6-allylphenol (114035-62-0)

Guidance literature:

at 70 - 75 ℃;

DOI:10.1134/S1070427207040295

Reference yield:

allyl p-tolyl ether (23431-48-3) → 4-methyl-2-(morpholinomethyl)-6-allylphenol (114035-62-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Heating

2: 65.2 percent / 70 - 75 °C

1: Claisen rearrangement / 2: Mannich reaction;

DOI:10.1134/S1070427207040295

Reference yield:

→ 4-methyl-2-(morpholinomethyl)-6-allylphenol (114035-62-0)

Guidance literature:

2-Allyl-4-methylphenol, CH2O, Morpholin;

upstream raw materials:

morpholine

formaldehyd

2-allyl-4-methylphenol

allyl p-tolyl ether

Refernces

• 1、 Magerramov,Bairamov,Mekhtieva,Agaeva,Mamedova,Kulieva,Mamedov. "Synthesis of aminomethylated derivatives of allylphenols and study of their antimicrobial characteristics in motor oil". . p. 665 - 668. Retrieved 2008/02/14.