N-acetyl-sulfanilic acid-[4]isoquinolylamide

Base Information

• Chemical Name: N-acetyl-sulfanilic acid-[4]isoquinolylamide
• CAS No.: 857622-00-5
• Molecular Formula: C₁₇H₁₅N₃O₃S
• Molecular Weight: 341.39
• Mol file: 857622-00-5.mol

Synonyms:

Chemical Property of N-acetyl-sulfanilic acid-[4]isoquinolylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-acetyl-sulfanilic acid-[4]isoquinolylamide

There total 2 articles about N-acetyl-sulfanilic acid-[4]isoquinolylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromoisoquinoline (1532-97-4) → N-acetyl-sulfanilic acid-[4]isoquinolylamide (857622-00-5)

Guidance literature:

Multi-step reaction with 2 steps

1: CuSO₄; aqueous NH₃ / 165 - 170 °C

2: pyridine

With pyridine; ammonium hydroxide; copper(II) sulfate;

DOI:10.1021/ja01256a012

Reference yield:

4-aminoisoquinoline (23687-25-4) + p-acetylaminobenzenesulfonyl chloride (121-60-8) → N-acetyl-sulfanilic acid-[4]isoquinolylamide (857622-00-5)

Guidance literature:

With pyridine;

DOI:10.1021/ja01256a012

Reference yield:

N-acetyl-sulfanilic acid-[4]isoquinolylamide (857622-00-5) → sulfanilic acid-[4]isoquinolylamide

Guidance literature:

With hydrogenchloride;

DOI:10.1021/ja01256a012

upstream raw materials:

4-aminoisoquinoline

p-acetylaminobenzenesulfonyl chloride

4-bromoisoquinoline