C₃₄H₅₁NO₆Si

Base Information

• Chemical Name: C₃₄H₅₁NO₆Si
• CAS No.: 244206-54-0
• Molecular Formula: C₃₄H₅₁NO₆Si
• Molecular Weight: 597.868
• Mol file: 244206-54-0.mol

Synonyms:

Chemical Property of C₃₄H₅₁NO₆Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₄H₅₁NO₆Si

There total 4 articles about C₃₄H₅₁NO₆Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-methylaniline (100-61-8) → C34H51NO6Si (244206-54-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 69 percent / tetramethylammonium bromide, MeOH, Br₂ / CH₂Cl₂

2: 1.) BuLi / 1.) THF, hexane, from -78 to -35 deg C, 5 min, 2.) THF, hexane, -78 deg C, 30 min

3: 1.) Mg, 2.) CuCl, 4.) aq. NH₄Cl

With methanol; n-butyllithium; bromine; tetramethylammonium bromide; ammonium chloride; magnesium; copper(l) chloride; In dichloromethane;

DOI:10.1016/S0039-128X(98)00086-5

Reference yield:

17α-hydroxy-19-norpregna-5(10),9(11)-diene-3,20-dione 3,20-bis(ethylene acetal) (54201-84-2) → C34H51NO6Si (244206-54-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 percent / hexafluoroacetone trihydrate, 30 wt percent aq. H₂O₂ / CH₂Cl₂ / 4 °C

2: 1.) Mg, 2.) CuCl, 4.) aq. NH₄Cl

With dihydrogen peroxide; ammonium chloride; magnesium; Hexafluoroacetone; copper(l) chloride; In dichloromethane;

DOI:10.1016/S0039-128X(98)00086-5

Reference yield:

4-bromo-N-methylaniline (6911-87-1,211060-12-7) → C34H51NO6Si (244206-54-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) BuLi / 1.) THF, hexane, from -78 to -35 deg C, 5 min, 2.) THF, hexane, -78 deg C, 30 min

2: 1.) Mg, 2.) CuCl, 4.) aq. NH₄Cl

With n-butyllithium; ammonium chloride; magnesium; copper(l) chloride;

DOI:10.1016/S0039-128X(98)00086-5

upstream raw materials:

5α,10α-epoxy-17α-hydroxy-19-norpregn-9(11)-ene-3,20-dione 3,20-bis(ethylene acetal)

4-bromo-N-methyl-N-trimethylsilylaniline

4-bromo-N-methylaniline

17α-hydroxy-19-norpregna-5(10),9(11)-diene-3,20-dione 3,20-bis(ethylene acetal)

Downstream raw materials:

17α-acetoxy-11β-(4-N-acetyl-N-methylaminophenyl)-19-norpregna-4,9-diene-3,20-dione

11β-(4-N-methylaminophenyl)-17α-hydroxy-19-norpregna-4,9-diene-3,20-dione

Refernces