CEFTAZIDIME IMPURITY A

Base Information

• Chemical Name: CEFTAZIDIME IMPURITY A
• CAS No.: 1000980-60-8
• Molecular Formula: C₂₂H₂₂N₆O₇S₂
• Molecular Weight: 546.585
• Mol file: 1000980-60-8.mol

Synonyms:

Chemical Property of CEFTAZIDIME IMPURITY A

Chemical Property:

• Melting Point: >136°C (dec.)
• Storage Temp.: Amber Vial, Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)

Purity/Quality:

≧95%, ^*data from raw suppliers

?2-Ceftazidime(>80%) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A Ceftazidime isomer, an impurity of Ceftazidime (C244100). 2-Ceftazidime, 90% (Ceftazidime EP Impurity A) is a Ceftazidime isomer, an impurity of Ceftazidime (C244100).

Technology Process of CEFTAZIDIME IMPURITY A

There total 1 articles about CEFTAZIDIME IMPURITY A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

ceftazidime (72558-82-8,97148-38-4,238093-13-5) → (6R,7R)-7-[2-(2-amino-4-thiazolyl)-2-(Z)-(2,2-dimethylacetoxyimino)acetamido]-3-[(pyridinium)methyl]-2-cephem-4-carboxylate (1000980-60-8,217796-42-4)

Guidance literature:

ceftazidime; With N-Trimethylsilylacetamide; In dichloromethane; for 0.5h;

With triethylamine; In dichloromethane; at 25 - 30 ℃; for 24h;

With hydrogenchloride; Further stages.;

upstream raw materials:

ceftazidime

Refernces