α-hydro-α-chlorooctafluoroethylbenzene

Base Information

• Chemical Name: α-hydro-α-chlorooctafluoroethylbenzene
• CAS No.: 5122-06-5
• Molecular Formula: C₈HClF₈
• Molecular Weight: 284.536
• Mol file: 5122-06-5.mol

Synonyms:

Chemical Property of α-hydro-α-chlorooctafluoroethylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-hydro-α-chlorooctafluoroethylbenzene

There total 3 articles about α-hydro-α-chlorooctafluoroethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

(1,1-dichloro-2,2,2-trifluoroethyl)pentafluorobenzene (5122-18-9) → α-hydro-α-chlorooctafluoroethylbenzene (5122-06-5) + 2,3,4,5,6-pentafluoro-(2,2-difluoroethenyl)benzene (653-19-0) + (2,2,2-trifluoroethyl)pentafluorobenzene (27059-24-1) + α-chloroheptafluorostyrene (58161-50-5)

Guidance literature:

With hydrogenchloride; zinc; In water; N,N-dimethyl-formamide; at 50 ℃; for 5h;

Reference yield:

2,3,4,5,6-pentafluorophenylmagnesium bromide (879-05-0) → α-hydro-α-chlorooctafluoroethylbenzene (5122-06-5)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / Heating

2: PCl₅

With phosphorus pentachloride; In diethyl ether;

DOI:10.1039/j39660000597

Reference yield:

Chlorodifluoromethane (75-45-6) + (1,1-dichloro-2,2,2-trifluoroethyl)pentafluorobenzene (5122-18-9) → α-hydro-α-chlorooctafluoroethylbenzene (5122-06-5) + decafluoro-α-methylstyrene (1996-63-0) + α-chloroheptafluorostyrene (58161-50-5)

Guidance literature:

at 620 ℃;

DOI:10.1016/S0022-1139(00)85196-9

upstream raw materials:

Chlorodifluoromethane

(1,1-dichloro-2,2,2-trifluoroethyl)pentafluorobenzene

2,3,4,5,6-pentafluorophenylmagnesium bromide

Refernces