Ethyl 2,4-dichloro-5-fluorobenzoate

Base Information

• Chemical Name: Ethyl 2,4-dichloro-5-fluorobenzoate
• CAS No.: 103318-75-8
• Molecular Formula: C9H7Cl2FO2
• Molecular Weight: 237.058
• Hs Code.: 2916399090
• DSSTox Substance ID: DTXSID50545451
• Wikidata: Q82422948
• Mol file: 103318-75-8.mol

Synonyms:ethyl 2,4-dichloro-5-fluorobenzoate;103318-75-8;Benzoic acid, 2,4-dichloro-5-fluoro-, ethyl ester;2,4-Dichloro-5-fluorobenzoic acid ethyl ester;SCHEMBL8335693;DTXSID50545451;MFCD06205036;ethyl 2,4-dichloro-5-fluoro-benzoate;CS-0364943

Chemical Property of Ethyl 2,4-dichloro-5-fluorobenzoate

Chemical Property:

• Vapor Pressure: 0.00301mmHg at 25°C
• Boiling Point: 284.3oC at 760 mmHg
• Flash Point: 116.2oC
• PSA: 26.30000
• Density: 1.378g/cm3
• LogP: 3.30920
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 235.9807130
• Heavy Atom Count: 14
• Complexity: 213

Purity/Quality:

99% ^*data from raw suppliers

2,4-Dichloro-5-fluorobenzoicacidethylester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C1=CC(=C(C=C1Cl)Cl)F

Technology Process of Ethyl 2,4-dichloro-5-fluorobenzoate

There total 6 articles about Ethyl 2,4-dichloro-5-fluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-dichloro-5-fluorobenzoyl chloride (86393-34-2) → 2,4-Dichloro-5-fluorobenzoic acid ethyl ester (103318-75-8)

Guidance literature:

In ethanol;

Reference yield:

diethyl ether (60-29-7,927820-24-4) + 2,4-dichloro-5-fluorobenzoyl chloride (86393-34-2) → 2,4-Dichloro-5-fluorobenzoic acid ethyl ester (103318-75-8)

Guidance literature:

In ethanol;

Reference yield:

diethyl ether (60-29-7,927820-24-4) + 2,4-dichloro-5-fluorobenzoyl chloride (86393-34-2) → ethyl 4-chloro-3-fluorobenzoate (203573-08-4) + 2,4-Dichloro-5-fluorobenzoic acid ethyl ester (103318-75-8)

Guidance literature:

In ethanol;

upstream raw materials:

ethanol

2,4-dichloro-5-fluorobenzoyl chloride

2,4-dichloro-5-fluoro-benzoic acid

diethyl ether

Downstream raw materials:

2,4-Dichloro-5-fluoro-benzoyl-acetonitrile

ethyl 2-chloro-4,5-difluorobenzoate

ethyl 4-chloro-3-fluorobenzoate

N-chloroacetyl-N'-(2,4-dichloro-5-fluorophenyl)hydrazine

Refernces

• 1、 Karthikeyan, Mari Sithambaram,Prasad, Dasappa Jagadeesh,Mahalinga, Manjathuru,Holla, Bantwal Shivarama,Kumari, Nalilu Suchetha. "Antimicrobial studies of 2,4-dichloro-5-fluorophenyl containing oxadiazoles". . p. 25 - 31. Retrieved 2008/09/18.
• 2、 -. "Method for preparing aromatic compounds". . . Retrieved 2008/06/13.