Dimethyloxosulfonium-3-ethoxycarbonyl-2-(p-tolyl)-allylid

Base Information

• Chemical Name: Dimethyloxosulfonium-3-ethoxycarbonyl-2-(p-tolyl)-allylid
• CAS No.: 19966-62-2
• Molecular Formula: C₁₅H₂₀O₃S
• Molecular Weight: 280.388
• Mol file: 19966-62-2.mol

Synonyms:

Chemical Property of Dimethyloxosulfonium-3-ethoxycarbonyl-2-(p-tolyl)-allylid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Dimethyloxosulfonium-3-ethoxycarbonyl-2-(p-tolyl)-allylid

There total 2 articles about Dimethyloxosulfonium-3-ethoxycarbonyl-2-(p-tolyl)-allylid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-(4-methylphenyl)prop-2-ynoate (52188-06-4) + trimethylsulfoxonium iodide (1774-47-6) → Dimethyloxosulfonium-3-ethoxycarbonyl-2-(p-tolyl)-allylid (19966-62-2)

Guidance literature:

Multistep reaction; (i) NaH, DMSO, (ii) /BRN= 2642197/;

DOI:10.1248/cpb.16.784

Reference yield:

→ Dimethyloxosulfonium-3-ethoxycarbonyl-2-(p-tolyl)-allylid (19966-62-2)

Guidance literature:

p-Toluolpropiolsaeure-ethylester, Dimethylsulfoxonium-methylid;

DOI:10.1016/S0040-4039(01)99797-7

Reference yield: 35.0%

Dimethyloxosulfonium-3-ethoxycarbonyl-2-(p-tolyl)-allylid (19966-62-2) + carbethoxyformonitrile oxide (51983-62-1) → (5-Ethoxy-3-p-tolyl-furan-2-yl)-[(E)-hydroxyimino]-acetic acid ethyl ester (77976-12-6)

Guidance literature:

With triethylamine; In tetrahydrofuran; for 0.5h; Ambient temperature;

DOI:10.1016/0040-4039(81)80129-3

upstream raw materials:

ethyl 3-(4-methylphenyl)prop-2-ynoate

trimethylsulfoxonium iodide

Downstream raw materials:

Dimethyloxosulfonium-1-phenylcarbamoyl-3-ethoxycarbonyl-2-(p-tolyl)-allylid

(5-Ethoxy-3-p-tolyl-furan-2-yl)-[(E)-hydroxyimino]-acetic acid ethyl ester

Refernces